Invasive fungal infections in children with cancer, neutropenia and fever, in Chile Infección micótica profunda en niños con cáncer, neutropenia y fiebre, en Chile.
Author
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Lucero, Yalda
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Brücher, Roberto
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Alvarez, Ana María
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Becker, Ana
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Cofré, José
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Enríquez, Nancy
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Payá, Ernesto
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Salgado, Carmen
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Santolaya de Pablo, María Elena
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Tordecilla, Juan
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Varas, Mónica
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Villarroel, Milena
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Viviani, Tamara
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Zubieta, Marcela
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O'Ryan Gallardo, Miguel
Admission date
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2019-01-29T17:51:47Z
Available date
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2019-01-29T17:51:47Z
Publication date
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2002
Cita de ítem
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Revista medica de Chile, Volumen 130, Issue 10, 2018, Pages 1139-1146
Identifier
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00349887
Identifier
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https://repositorio.uchile.cl/handle/2250/163566
Abstract
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BACKGROUND: Invasive fungal infections (IFI) cause prolonged hospitalizations and increase the possibility of death among patients with cancer and febrile neutropenia (FN). Up to 10% of febrile neutropenic episodes may be caused by IFI. AIM: To estimate the incidence of IFI among a large group of Chilean children with cancer and FN. PATIENTS AND METHODS: Clinical and laboratory information was collected from a data base provided by the "Programa Infantil Nacional de Drogas Antineoplásicas" (PINDA) that included 445 FN episodes occurring in five hospitals in Santiago, Chile. This information was used to identify children that presented with signs and symptoms compatible with an IFI. According to predefined criteria based on a literature review, IFI episodes were categorized as "proven", "probable" or "possible". RESULTS: A total of 41/445 episodes (9.2%) were compatible with an IFI of which 4 (0.9%) were proven, 23 (5.2%) probable, and 14 (3.1%) possible. Hospitalization was longer (27
Invasive fungal infections in children with cancer, neutropenia and fever, in Chile Infección micótica profunda en niños con cáncer, neutropenia y fiebre, en Chile.