Spontaneous growth of 83 Chilean girls with Turner's syndrome Síndrome de Turner: Crecimiento y descripción clínica en 83 niñas chilenas
Author
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Román, Rossana
Author
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Vallejos, María Eliana
Author
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Muñoz, Mónica
Author
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Schneider, Ruth
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Youlton, Ronald
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Henriquez, Cecilia
Author
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Cassorla Goluboff, Fernando
Admission date
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2019-01-29T17:51:59Z
Available date
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2019-01-29T17:51:59Z
Publication date
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2002
Cita de ítem
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Revista Medica de Chile, Volumen 130, Issue 9, 2018, Pages 977-984
Identifier
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00349887
Identifier
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https://repositorio.uchile.cl/handle/2250/163630
Abstract
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Background: Short stature is the main feature of patients with Turner's syndrome. There is limited information regarding the spontaneous growth of these patients in Chile. Aim: To develop a specific growth chart for Chilean patients with Turner's syndrome. Material and methods: We retrospectively analyzed 668 height measurements from 85 Chilean girls, born after 1968, with 45XO karyotype (minimum 15%), and without an Y chromosome fragment. Patients with hormonal therapy, such as growth hormone or estrogen, except thyroid hormone replacement, were excluded. Results: The karyotypes were 60% 45XO, 25% 45XO, 46XX, and 15% other complex mosaics. The birth length was 46.8 ± 2.1 cm. The final height of our patients was 138,20 ± 7,0 cm. Conclusions: The final height achieved by our patients, is similar to Argentinian and Japanese patients, but is below the mean stature reported for Scandinavian and Northamerican patients who achieve a mean adult height of approximately 147, and 142 cm respecti