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Genetic variation and population structure in Native Americans

Authordc.contributor.authorWang, Sijia 
Authordc.contributor.authorLewis, Cecil M. 
Authordc.contributor.authorJakobsson, Mattias 
Authordc.contributor.authorRamachandran, Sohini 
Authordc.contributor.authorRay, Nicolas 
Authordc.contributor.authorBedoya, Gabriel 
Authordc.contributor.authorRojas, Winston 
Authordc.contributor.authorParra, Maria V. 
Authordc.contributor.authorMolina, Julio A. 
Authordc.contributor.authorGallo, Carla 
Authordc.contributor.authorMazzotti, Guido 
Authordc.contributor.authorPoletti, Giovanni 
Authordc.contributor.authorHill, Kim 
Authordc.contributor.authorHurtado, Ana M. 
Authordc.contributor.authorLabuda, Damian 
Authordc.contributor.authorKlitz, William 
Authordc.contributor.authorBarrant 
Admission datedc.date.accessioned2019-03-11T12:55:04Z
Available datedc.date.available2019-03-11T12:55:04Z
Publication datedc.date.issued2007
Cita de ítemdc.identifier.citationPLoS Genetics, Volumen 3, Issue 11, 2018, Pages 2049-2067
Identifierdc.identifier.issn15537404
Identifierdc.identifier.issn15537390
Identifierdc.identifier.other10.1371/journal.pgen.0030185
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/164454
Abstractdc.description.abstractWe examined genetic diversity and population structure in the American landmass using 678 autosomal microsatellite markers genotyped in 422 individuals representing 24 Native American populations sampled from North, Central, and South America. These data were analyzed jointly with similar data available in 54 other indigenous populations worldwide, including an additional five Native American groups. The Native American populations have lower genetic diversity and greater differentiation than populations from other continental regions. We observe gradients both of decreasing genetic diversity as a function of geographic distance from the Bering Strait and of decreasing genetic similarity to Siberians - signals of the southward dispersal of human populations from the northwestern tip of the Americas. We also observe evidence of: (1) a higher level of diversity and lower level of population structure in western South America compared to eastern South America, (2) a relative lack of diffe
Lenguagedc.language.isoen
Publisherdc.publisherPublic Library of Science
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Sourcedc.sourcePLoS Genetics
Keywordsdc.subjectEcology, Evolution, Behavior and Systematics
Keywordsdc.subjectMolecular Biology
Keywordsdc.subjectGenetics
Keywordsdc.subjectGenetics (clinical)
Keywordsdc.subjectCancer Research
Títulodc.titleGenetic variation and population structure in Native Americans
Document typedc.typeArtículo de revista
Catalogueruchile.catalogadorSCOPUS
Indexationuchile.indexArtículo de publicación SCOPUS
uchile.cosechauchile.cosechaSI


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile