Show simple item record

Genetic variation and population structure in Native Americans

Authordc.contributor.authorWang, Sijia 
Authordc.contributor.authorLewis, Cecil M. 
Authordc.contributor.authorJakobsson, Mattias 
Authordc.contributor.authorRamachandran, Sohini 
Authordc.contributor.authorRay, Nicolas 
Authordc.contributor.authorBedoya, Gabriel 
Authordc.contributor.authorRojas, Winston 
Authordc.contributor.authorParra, Maria V. 
Authordc.contributor.authorMolina, Julio A. 
Authordc.contributor.authorGallo, Carla 
Authordc.contributor.authorMazzotti, Guido 
Authordc.contributor.authorPoletti, Giovanni 
Authordc.contributor.authorHill, Kim 
Authordc.contributor.authorHurtado, Ana M. 
Authordc.contributor.authorLabuda, Damian 
Authordc.contributor.authorKlitz, William 
Cita de ítemdc.identifier.citationPLoS Genetics, Volumen 3, Issue 11, 2018, Pages 2049-2067
Abstractdc.description.abstractWe examined genetic diversity and population structure in the American landmass using 678 autosomal microsatellite markers genotyped in 422 individuals representing 24 Native American populations sampled from North, Central, and South America. These data were analyzed jointly with similar data available in 54 other indigenous populations worldwide, including an additional five Native American groups. The Native American populations have lower genetic diversity and greater differentiation than populations from other continental regions. We observe gradients both of decreasing genetic diversity as a function of geographic distance from the Bering Strait and of decreasing genetic similarity to Siberians - signals of the southward dispersal of human populations from the northwestern tip of the Americas. We also observe evidence of: (1) a higher level of diversity and lower level of population structure in western South America compared to eastern South America, (2) a relative lack of diffe
Publisherdc.publisherPublic Library of Science
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.uri
Sourcedc.sourcePLoS Genetics
Keywordsdc.subjectEcology, Evolution, Behavior and Systematics
Keywordsdc.subjectMolecular Biology
Keywordsdc.subjectGenetics (clinical)
Keywordsdc.subjectCancer Research
Títulodc.titleGenetic variation and population structure in Native Americans
Document typedc.typeArtículo de revista
Indexationuchile.indexArtículo de publicación SCOPUS

Files in this item


This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile