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Metabolic profile in sons of women with polycystic ovary syndrome

Authordc.contributor.authorRecabarren, Sergio E. 
Authordc.contributor.authorSmith, Rosita 
Authordc.contributor.authorRios, Rafael 
Authordc.contributor.authorMaliqueo Yevilao, Manuel 
Authordc.contributor.authorEchiburú López, Bárbara 
Authordc.contributor.authorCodner Dujovne, Ethel 
Authordc.contributor.authorCassorla Goluboff, Fernando 
Authordc.contributor.authorRojas, Pedro 
Authordc.contributor.authorSir Petermann, Teresa 
Admission datedc.date.accessioned2019-03-11T12:55:47Z
Available datedc.date.available2019-03-11T12:55:47Z
Publication datedc.date.issued2008
Cita de ítemdc.identifier.citationJournal of Clinical Endocrinology and Metabolism, Volumen 93, Issue 5, 2018, Pages 1820-1826
Identifierdc.identifier.issn0021972X
Identifierdc.identifier.issn0021972X
Identifierdc.identifier.other10.1210/jc.2007-2256
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/164513
Abstractdc.description.abstractContext: Polycystic ovary syndrome (PCOS) is a common endocrine-metabolic disorder with strong familial aggregation. It has been demonstrated that parents and brothers of PCOS women exhibit insulin resistance and related metabolic defects. However, metabolic phenotypes in sons of PCOS women have not been described. Objective: Our objective was to assess the metabolic profiles in sons of women with PCOS during different stages of life: early infancy, childhood, and adulthood. Design: Eighty sons of women with PCOS (PCOSS) and 56 sons of control women without hyperandrogenism (CS), matched for age, were studied. In early infancy, glucose and insulin were determined in the basal sample. In children and adults, a 2-h oral glucose tolerance test was performed with measurements of glucose and insulin. Adiponectin, leptin, C-reactive protein, SHBG, and serum lipids were determined in the basal sample during the three periods. Results: During early infancy, PCOSS showed higher weight (P = 0.03
Lenguagedc.language.isoen
Publisherdc.publisherEndocrine Society
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Sourcedc.sourceJournal of Clinical Endocrinology and Metabolism
Keywordsdc.subjectEndocrinology, Diabetes and Metabolism
Keywordsdc.subjectBiochemistry
Keywordsdc.subjectEndocrinology
Keywordsdc.subjectClinical Biochemistry
Keywordsdc.subjectBiochemistry (medical)
Títulodc.titleMetabolic profile in sons of women with polycystic ovary syndrome
Document typedc.typeArtículo de revista
Catalogueruchile.catalogadorSCOPUS
Indexationuchile.indexArtículo de publicación SCOPUS
uchile.cosechauchile.cosechaSI


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile