Bacteriological quality of air in a ward for sterile pharmaceutical preparations Calidad microbiológica del aire de una unidad de preparados farmacéuticos estériles
Author
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Caorsi P., Beatriz
Author
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Sakurada Z., Andrea
Author
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Ulloa F., M. Teresa
Author
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Pezzani V., Marcela
Author
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Latorre O., Paz
Admission date
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2019-03-11T13:01:39Z
Available date
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2019-03-11T13:01:39Z
Publication date
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2011
Cita de ítem
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Revista Chilena de Infectologia, Volumen 28, Issue 1, 2018, Pages 14-18
Identifier
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07161018
Identifier
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https://repositorio.uchile.cl/handle/2250/165231
Abstract
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Background: An extremely clean area is required for preparation of sterile pharmaceutical compounds, in compliance with international standards, to minimize the probability of microbial contamination. Aim: To evaluate the bacteriological quality of the air in the Sterile Pharmaceutical Preparation Unit of the University of Chile's Clinical Hospital and to set up alerts and action levels of bacterial growth. Methods: We studied eight representative sites of our Unit on a daily basis from January to February 2005 and twice a week from June 2005 to February 2006. We collected 839 samples of air by impact in the Petri dish. Results: 474 (56.5%) samples were positive; 17 (3.5%) of them had an inappropriate bacterial growth (2% of total samples). The samples from sites 1 and 2 (big and small biosafety cabinets) were negative. The countertop and transfer area occasionally exceeded the bacterial growth limits. The most frequently isolated bacteria were coagulase-negative staphylococci. Microco
Bacteriological quality of air in a ward for sterile pharmaceutical preparations Calidad microbiológica del aire de una unidad de preparados farmacéuticos estériles