Caregiver burden in amyotrophic lateral sclerosis is more dependent on patients' behavioral changes than physical disability: A comparative study
Author
dc.contributor.author
Lillo, Patricia
Author
dc.contributor.author
Mioshi, Eneida
Author
dc.contributor.author
Hodges, John R.
Admission date
dc.date.accessioned
2019-03-15T16:03:32Z
Available date
dc.date.available
2019-03-15T16:03:32Z
Publication date
dc.date.issued
2012
Cita de ítem
dc.identifier.citation
BMC Neurology, Volumen 12,
Identifier
dc.identifier.issn
14712377
Identifier
dc.identifier.other
10.1186/1471-2377-12-156
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/165853
Abstract
dc.description.abstract
Background: Behavioral changes in patients with amyotrophic lateral sclerosis (ALS) mirror those found in frontotemporal dementia (FTD). Considering the high rate of neuropsychiatric symptoms found in ALS patients, this paper examines whether caregiver burden is associated with behavioral changes over and above the physical disability of patients with ALS, and if the presence of caregivers' depression, anxiety and stress also impacts on caregiver burden.Methods: 140 caregivers of patients with ALS participated in a postal survey investigating patients' neuropsychiatric symptoms (Cambridge Behaviour Inventory Revised CBI-R), motor function (Amyotrophic Lateral Sclerosis Functional Rating Scale Revised - ALSFRS-R), caregiver burden (Zarit Burden Interview), and caregiver mood (Depression, Anxiety and Stress Scale- DASS21). Seventy four percent of them were caregivers of patients with limb onset and 25.7% were caregivers of patients with bulbar onset. Results: Moderate to severe behaviora