Effects of malathion on cellularity and sperm differentiation in testis and epididymis of adult rats Efectos del malatión en la celularidad y diferenciación de espermatozoides en testículo y epidídimo de ratas adultas
Author
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Espinoza-Navarro, Omar
Author
dc.contributor.author
Bustos-Obregón, E.
Admission date
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2019-03-15T16:06:37Z
Available date
dc.date.available
2019-03-15T16:06:37Z
Publication date
dc.date.issued
2014
Cita de ítem
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International Journal of Morphology, Volumen 32, Issue 1, 2018, Pages 119-124
Identifier
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07179502
Identifier
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07179367
Identifier
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10.4067/S0717-95022014000100020
Identifier
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https://repositorio.uchile.cl/handle/2250/166164
Abstract
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Malathion is an organophosphorous insecticide, used worldwide for pest and disease control; however, it could also affect the reproductive patterns of several species. The aim of this study was to determine the effects of malathion in the cellularity and sperm differentiation in testis and epididymis of rats. Twenty adult male Sprague Dawley rats were divided into a malathion-treated group (n=10, dose of 170 mg/kg via subcutaneous injection for a period of 13 days) and control group (n=10, injected only with normal saline). After treatments, the rats were sacrificed by regulated euthanasia and assessed for sperm count in testis and epididymis and epididymal teratospermia degree. The results showed a significant decrease in body, testicular and epididymal weight in animals treated with malathion. Testicular sperm counts in treated rats exhibited a significant decrease in the number of sperm compared to controls (42.56×106 vs. 95.99×106), as well as in epididymis (77.55×106 vs. 106.54×10
Effects of malathion on cellularity and sperm differentiation in testis and epididymis of adult rats Efectos del malatión en la celularidad y diferenciación de espermatozoides en testículo y epidídimo de ratas adultas