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Author | dc.contributor.author | Basualto-Alarcón, Carla | |
Author | dc.contributor.author | Varela, Diego | |
Author | dc.contributor.author | Duran, Javier | |
Author | dc.contributor.author | Maass, Rodrigo | |
Author | dc.contributor.author | Estrada, Manuel | |
Admission date | dc.date.accessioned | 2019-03-15T16:07:35Z | |
Available date | dc.date.available | 2019-03-15T16:07:35Z | |
Publication date | dc.date.issued | 2014 | |
Cita de ítem | dc.identifier.citation | Frontiers in Endocrinology, Volumen 5, Issue DEC, 2018, | |
Identifier | dc.identifier.issn | 16642392 | |
Identifier | dc.identifier.other | 10.3389/fendo.2014.00217 | |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/166245 | |
Abstract | dc.description.abstract | © 2014 Basualto-Alarcón, Varela, Duran, Maass and Estrada.Sarcopenia, the age-related loss of skeletal muscle mass and function, is becoming more prevalent as the lifespan continues to increase in most populations. As sarcopenia is highly disabling, being associated with increased risk of dependence, falls, fractures, weakness, disability, and death, development of approaches to its prevention and treatment are required. Androgens are the main physiologic anabolic steroid hormones and normal testosterone levels are necessary for a range of developmental and biological processes, including maintenance of muscle mass. Testosterone concentrations decline as age increase, suggesting that low plasma testosterone levels can cause or accelerate muscle- and age-related diseases, as sarcopenia. Currently, there is increasing interest on the anabolic properties of testosterone for therapeutic use in muscle diseases including sarcopenia. However, the pathophysiological mechanisms underlying this | |
Lenguage | dc.language.iso | en | |
Publisher | dc.publisher | Frontiers Media S.A. | |
Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
Source | dc.source | Frontiers in Endocrinology | |
Keywords | dc.subject | Androgen deficiency | |
Keywords | dc.subject | Elderly | |
Keywords | dc.subject | Sarcopenia | |
Keywords | dc.subject | Skeletal muscle | |
Keywords | dc.subject | Testosterone | |
Título | dc.title | Sarcopenia and androgens: A link between pathology and treatment | |
Document type | dc.type | Artículo de revista | |
dcterms.accessRights | dcterms.accessRights | Acceso Abierto | |
Cataloguer | uchile.catalogador | SCOPUS | |
Indexation | uchile.index | Artículo de publicación SCOPUS | |
uchile.cosecha | uchile.cosecha | SI | |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile