Impact of living and socioeconomic characteristics on cardiovascular risk in ischemic stroke patients
Author
dc.contributor.author
Amarenco, Pierre
Author
dc.contributor.author
Abboud, Halim
Author
dc.contributor.author
Labreuche, Julien
Author
dc.contributor.author
Arauz, Antonio
Author
dc.contributor.author
Bryer, Alan
Author
dc.contributor.author
Lavados Germain, Pablo Manuel
Author
dc.contributor.author
Massaro, Ayrton
Author
dc.contributor.author
Muñoz Collazos, Mario
Author
dc.contributor.author
Steg, Philippe Gabriel
Author
dc.contributor.author
Yamout, Bassem I.
Author
dc.contributor.author
Vicaut, Eric
Admission date
dc.date.accessioned
2019-03-15T16:08:56Z
Available date
dc.date.available
2019-03-15T16:08:56Z
Publication date
dc.date.issued
2014
Cita de ítem
dc.identifier.citation
International Journal of Stroke, Vol 9, December 2014, 1065–1072
Identifier
dc.identifier.issn
17474949
Identifier
dc.identifier.issn
17474930
Identifier
dc.identifier.other
10.1111/ijs.12290
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/166377
Abstract
dc.description.abstract
Objective We aimed to stratify the risk of vascular event recurrence in patients with cerebral infarction according to living
and socioeconomic characteristics and geographic region.
Method The Outcomes in Patients with TIA and Cerebrovascular Disease (OPTIC) study is an international prospective
study of patients aged 45 years or older who required secondary prevention of stroke [following either an acute transient
ischemic attack, minor ischemic strokes, or recent (less than
six-months previous), stable, first-ever, nondisabling ischemic
stroke]. A total 3635 patients from 245 centers in 17 countries
in four regions (Latin America, Middle East, North Africa, South
Africa) were enrolled between 2007 and 2008. The outcome
measure was the two-year rate of a composite of major vascular events (vascular death, myocardial infarction and stroke).
Results During the two-year follow-up period, 516 patients
experienced at least one major cardiovascular event, resulting
in an event rate of 15·6% (95% confidence interval 14·4–
16·9%). Event rates varied across geographical region
(P < 0·001), ranging from 13·0% in Latin America to 20·7% in
North Africa. Unemployment status, living in a rural area, not
living in fully serviced accommodation (i.e., house or apartment with its own electricity, toilet and water supply), no
health insurance coverage, and low educational level (less
than two-years of schooling) were predictors of major vascular
events. Major vascular event rates steeply increased with the
number of low-quality living/socioeconomic conditions (from
13·4% to 47·9%, adjusted P value for trend <0·001).
Conclusion Vascular risk in stroke patients in low- and middleincome countries varies not only with the number of arterial
beds involved but also with socioeconomic variables.