Intracerebral Stem Cell Administration Inhibits Relapse-like Alcohol Drinking in Rats
| Author | dc.contributor.author | Israel Jacard, Yedy | |
| Author | dc.contributor.author | Ezquer, Fernando | |
| Author | dc.contributor.author | Quintanilla González, María Elena | |
| Author | dc.contributor.author | Morales, Paola | |
| Author | dc.contributor.author | Ezquer, Marcelo | |
| Author | dc.contributor.author | Herrera-Marschitz Muller, Mario | |
| Admission date | dc.date.accessioned | 2019-03-18T11:55:38Z | |
| Available date | dc.date.available | 2019-03-18T11:55:38Z | |
| Publication date | dc.date.issued | 2017 | |
| Cita de ítem | dc.identifier.citation | Alcohol and alcoholism (Oxford, Oxfordshire), Volumen 52, Issue 1, 2018, Pages 1-4 | |
| Identifier | dc.identifier.issn | 14643502 | |
| Identifier | dc.identifier.other | 10.1093/alcalc/agw068 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/167019 | |
| Abstract | dc.description.abstract | © The Author 2016. Medical Council on Alcohol and Oxford University Press. All rights reserved. Study describes the blockade of relapse-like alcohol drinking by mesenchymal stem cells (MSCs). High alcohol-intake bred rats consumed alcohol for 3 months and were subjected to repeated alcohol deprivations for 7-14 days, followed by alcohol reaccess. Upon reaccess, animals consumed 2.2 g alcohol/kg in 60 minutes. A single intra-cerebroventricular MSC administration inhibited relapse-like drinking up to 80-85% for 40 days (P < 0.001). An alcohol-use-disorder was prevented. | |
| Lenguage | dc.language.iso | en | |
| Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
| Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
| Source | dc.source | Alcohol and alcoholism (Oxford, Oxfordshire) | |
| Keywords | dc.subject | Medicine (miscellaneous) | |
| Keywords | dc.subject | Medicine (all) | |
| Keywords | dc.subject | Toxicology | |
| Keywords | dc.subject | Psychiatry and Mental Health | |
| Título | dc.title | Intracerebral Stem Cell Administration Inhibits Relapse-like Alcohol Drinking in Rats | |
| Document type | dc.type | Artículo de revista | |
| dcterms.accessRights | dcterms.accessRights | Acceso Abierto | |
| Cataloguer | uchile.catalogador | SCOPUS | |
| Indexation | uchile.index | Artículo de publicación SCOPUS | |
| uchile.cosecha | uchile.cosecha | SI |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile