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Author dc.contributor.author Honda, Luis
Author dc.contributor.author Becerra Herrera, Mercedes
Author dc.contributor.author Richter Duk, Pablo
Admission date dc.date.accessioned 2019-03-18T12:03:50Z
Available date dc.date.available 2019-03-18T12:03:50Z
Publication date dc.date.issued 2018
Cita de ítem dc.identifier.citation Analytical and Bioanalytical Chemistry, Volumen 410, Issue 30, 2018, Pages 7909-7919
Identifier dc.identifier.issn 16182650
Identifier dc.identifier.issn 16182642
Identifier dc.identifier.other 10.1007/s00216-018-1412-0
Identifier dc.identifier.uri https://repositorio.uchile.cl/handle/2250/167684
Abstract dc.description.abstract © 2018, Springer-Verlag GmbH Germany, part of Springer Nature. A method combining liquid chromatography with a dual-probe ultraspray electrospray ionization (ESI) source and time-of-flight high-resolution mass spectrometry (LC-ESI-TOF/MS) was developed for the simultaneous determination of four steroidal sex hormones, estrone (E1), 17β-estradiol (E2), 17α-ethinyl estradiol (EE2), and estriol (E3), as well as five of their hydroxylated metabolites, 2-hydroxyestrone (2-OHE1), 4-hydroxyestrone (4-OHE1), 16α-hydroxyestrone (16-OHE1), 2-hydroxyestradiol (2-OHE2), and 4-hydroxyestradiol (4-OHE2), in water samples in a short chromatographic run of 10 min. Derivatization of the analytes was optimized using dansyl chloride as the derivatizing agent. Under optimal positive ionization conditions, the following signals, which had not been previously reported, were observed (with theoretical values of m/z 377.1373 for 2- and 4-OHE1 and 378.1452 for 2- and 4-OHE2), corresponding to doubly derivatize
Lenguage dc.language.iso en
Publisher dc.publisher Springer Verlag
Type of license dc.rights Attribution-NonCommercial-NoDerivs 3.0 Chile
Link to License dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Source dc.source Analytical and Bioanalytical Chemistry
Keywords dc.subject Catechol estrogens
Keywords dc.subject Derivatization reaction
Keywords dc.subject Estrogenic hormones
Keywords dc.subject LC-ESI-TOF/MS
Keywords dc.subject Positive electrospray ionization
Keywords dc.subject Wastewater
Título dc.title Liquid chromatography–time-of-flight high-resolution mass spectrometry study and determination of the dansylated products of estrogens and their hydroxylated metabolites in water and wastewater
Document type dc.type Artículo de revista
Cataloguer uchile.catalogador SCOPUS
Indexation uchile.index Artículo de publicación SCOPUS
uchile.cosecha uchile.cosecha SI
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