Changes in muscle activity patterns and joint kinematics during gait in hemophilic arthropathy
Author
dc.contributor.author
Cruz Montecinos, Carlos
Author
dc.contributor.author
Pérez Alenda, Sofía
Author
dc.contributor.author
Querol, Felipe
Author
dc.contributor.author
Cerda Villablanca, Mauricio
Author
dc.contributor.author
Maas, Huub
Admission date
dc.date.accessioned
2020-05-07T15:08:33Z
Available date
dc.date.available
2020-05-07T15:08:33Z
Publication date
dc.date.issued
2020
Cita de ítem
dc.identifier.citation
Front Physiol. January 2020 | Volume 10 | Article 1575
es_ES
Identifier
dc.identifier.other
10.3389/fphys.2019.01575
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/174499
Abstract
dc.description.abstract
Hemophilic arthropathy is the result of repetitive intra-articular bleeding and synovial inflammation. In people with hemophilic arthropathy (PWHA), very little is known about the neural control of individual muscles during movement. The aim of the present study was to assess if the neural control of individual muscles and coordination between antagonistic muscle pairs and joint kinematics during gait are affected in PWHA. Thirteen control subjects (CG) walked overground at their preferred and slow velocity (1 m/s), and 14 PWHA walked overground at the preferred velocity (1 m/s). Joint kinematics and temporal gait parameters were assessed using four inertial sensors. Surface electromyography (EMG) was collected from gluteus maximus (GMAX), gluteus medius (GMED), vastus medialis (VM), vastus lateralis (VL), rectus femoris (RF), medial gastrocnemius (MG), lateral gastrocnemius (LG), soleus (SOL), tibialis anterior (TA), semitendinosus (ST), and biceps femoris (BF). Waveforms were compared using the time-series analysis through statistical parametric mapping. In PWHA compared to CG, EMG amplitude during the stance phase was higher for LG (for both velocities of the CG), BF (slow velocity only), and ST (preferred velocity only) (p < 0.05). Co-contraction during the stance phase was higher for MG-TA, LG-TA, VL-BF, VM-ST, LG-VL, and MG-VM (both velocities) (p < 0.05). MG and LG were excited earlier (preferred velocity only) (p < 0.05). A later offset during the stance phase was found for VL, BF, and ST (both velocities), and BF and GMAX (preferred velocity only) (p < 0.05). In addition, the range of motion in knee and ankle joints was lower in PWHA (both velocities) and hip joint (preferred velocity only) (p < 0.05). In conclusion, the neural control of individual muscles and coordination between antagonistic muscles during gait in PWHA differs substantially from control subjects.
es_ES
Patrocinador
dc.description.sponsorship
Chilean National Commission for Scientific and Technological Research (RING Initiative)
ACT192015
Chilean National Commission for Scientific and Technological Research (FONDEQUIP)
EQM140119
Comision Nacional de Investigacion Cientifica y Tecnologica (CONICYT)
CONICYT FONDECYT
1181823
1180906
Chilean Millennium Science Initiative
P09-015-F