Now showing items 21-40 of 106

    • Bollo Dragnic, Soledad; Núñez Vergara, Luis; Squella Serrano, Juan (1999)
      Cyclic voltammetry (CV) and digital simulation methods are utilized to elucidate the mechanism of electrochemical reduction of a series of nitro aryl 1,4-dihydropyridines in protic (aqueous) and mixed media. The experimental ...
    • Mozo, J. D.; Carbajo, J.; Sturm Schaub, Juan; Núñez Vergara, Luis; Salgado, P.; Squella Serrano, Juan (Wiley, 2012)
      A new, sensitive, reproducible and easy-to-use flow-injection method for determining nifuroxazide based on adsorptive stripping linear sweep voltammetry over screen-printed carbon electrodes is presented. The presented ...
    • Yáñez,; Núñez Vergara, Luis; Squella Serrano, Juan (2002)
      Carbon paste electrodes modified with β-cyclodextrin have been investigated for voltammetric determination of nitrendipine. The immobilization of the β-cyclodextrin on the carbon paste leads to a modification of the electrode ...
    • Yáñez, C.; Núñez Vergara, Luis; Squella Serrano, Juan (2003)
      The formation of inclusion complexes of well-known 1,4-dihydropyridine calcium antagonists, such as nifedipine (NF) and nicardipine (NC), with beta-cyclodextrin (betaCD) was investigated by differential pulse polarography ...
    • Squella Serrano, Juan; Borges, Y.; Bobadilla, L.; Núñez Vergara, Luis (1990)
      A new differential pulse polarographic method for the determination of buspirone pharmaceutical formulations is proposed. The method is based on the CN bond electroactivity of buspirone pirimidinic ring. Recovery study ...
    • Núñez Vergara, Luis; Pardo Jiménez, V; Barrientos, C.; Olea Azar, Claudio; Navarrete-Encina, P. A.; Squella Serrano, Juan (2012)
      In this study, two series of dihydropyridine-fused and pyridine-fused coumarins were synthesised and electrochemically characterised in aprotic medium. In both series, the most easily reducible groups were the endocyclic ...
    • Maya Arango, Juan; Morello Casté, Antonio; Repetto Scaramelli, Yolanda; Tellez Neubauer, Rowena; Rodríguez, A.; Zelada, U.; Puebla, P.; Caballero S., Esther; Medarde, M.; Núñez Vergara, Luis; Squella Serrano, Juan; Bontá, M.; Bollo Dragnic, Soledad; Feliciano M., Arturo San (PERGAMON-ELSEVIER SCIENCE, 2000-01)
      A series of 3-chloro-phenyl-1,4-dihydropyridine derivatives produced different degrees of inhibition of parasite growth and respiration on clone Brener, LQ and Tulahuen strains of Trypanosome cruzi epimastigotes. Respiratory ...
    • Núñez Vergara, Luis; López Alarcón, Camilo; Navarrete Encina, Patricio; Atria Salas, Ana María; Camargo Grandón, Rodrigo; Squella Serrano, Juan (TAYLOR & FRANCIS LTD, 2003)
      This work reports the electrochemical oxidation of a series of three synthesized 4-substituted-1,4-dihydropyridine derivatives in different electrolytic media. Also, an EPR characterization of intermediates and the reactivity ...
    • Núñez Vergara, Luis; Santander Gutiérrez, Ingrid Paola; Navarrete Encina, Patricio; Valenzuela Pedevila, Jorge; Sturm Schaub, Juan; Squella Serrano, Juan (ELECTROCHEMICAL SOC, 2006)
      The present paper deals with the electrochemical and electron spin resonance (ESR) characterization of a number of nitroso phenyl 1,4-dihydropyridines in aprotic media on a hanging drop mercury electrode (HDME). The ...
    • Bollo Dragnic, Soledad; Muñoz, L.; Núñez Vergara, Luis; Squella Serrano, Juan (WILEY-V C H VERLAG GMBH, 2000-03)
      Tacrine, 9-amino-1,2,3,4-tetrahydroacridine, an antialzheimer's disease agent was electrochemically studied and a polarographic method For its quantitative determination in pharmaceuticals was developed. Tacrine was ...
    • Bollo Dragnic, Soledad; Muñoz,; Núñez Vergara, Luis; Squella Serrano, Juan (2000)
      Tacrine, 9-amino-1,2,3,4-tetrahydroacridine, an antialzheimer's disease agent was electrochemically studied and a polarographic method for its quantitative determination in pharmaceuticals was developed. Tacrine was ...
    • Squella Serrano, Juan; Iribarren, Anny E.; Sturm, Juan C.; Núñez Vergara, Luis (1999)
      Lacidipine is an antihypertensive drug that is oxidizable at the glassy carbon electrode. The voltammetric oxidation of lacidipine in aqueous-alcoholic solutions (70 + 30) produces a well-defined voltammetric peak when ...
    • Núñez Vergara, Luis; Farías Oddone, Daniel Rodrigo; Bollo Dragnic, Soledad; Squella Serrano, Juan (ELSEVIER SCIENCE, 2001-01)
      This paper reports the feasibility of free radicals formation from flutamide by using cyclic voltammetry. The electrochemical characteristics and the reactivity of the one-electron reduction product from flutamide in mixed ...
    • Núñez Vergara, Luis; Ortiz, Luis J.; Bollo Dragnic, Soledad; Squella Serrano, Juan (1997)
      This paper reports a comprehensive study by cyclic voltammetry on the electrochemical characteristics and the reactivity of the one-electron reduction product from a series of nitro aryl 1,4-dihydropyridines in mixed and ...
    • Squella Serrano, Juan; Cassels Niven, Bruce; Arata, M.; Bavestrello, M. P.; Núñez Vergara, Luis (Pergamon Press Ltd., 1993-03-23)
      Four amphetamine derivatives bearing a methylenedioxy group at positions 3 and 4 of the benzene ring and differing in their substitution at C(6) were studied by differential pulse voltammetry in aqueous media. These ...
    • Squella Serrano, Juan; Cassels Niven, Bruce; Arata, M.; Bavestrello, M. P.; Núñez Vergara, Luis (1993)
      Four amphetamine derivatives bearing a methylenedioxy group at positions 3 and 4 of the benzene ring and differing in their substitution at C(6) were studied by differential pulse voltammetry in aqueous media. These ...
    • Núñez Vergara, Luis; Santander, Paola; Navarrete Encina, Patricio; Squella Serrano, Juan (ELSEVIER, 2005-06-15)
      A comprehensive study of the electrochemical reduction in protic media of parent C-4 nitrophenyl 1,4-DHPs and their corresponding nitrosophenyl 1,4-DHPs was carried out. The reduction potentials of synthesized aromatic ...
    • Sturm, J. C.; Núñez Vergara, Luis; Squella Serrano, Juan (1992)
      Electrochemical reduction of nicergoline was studied at different pH and concentrations using differential pulse polarography and linear sweep voltammetry. Both techniques reveal that the reduction process occurs with ...
    • Núñez Vergara, Luis; Bontá, M.; Sturm Schaub, Juan; Navarrete Encina, Patricio; Bollo Dragnic, Soledad; Squella Serrano, Juan (ELSEVIER SCIENCE, 2001-06-15)
      A comprehensive study of the electrochemical reduction, in different electrolytic media, of two nitroso compounds, i.e. ortho- and meta-nitrosotoluene derivatives has been carried out. Furthermore, UV-vis and EPR spectroscopic ...
    • Squella Serrano, Juan; Huerta, M; Bollo Dragnic, Soledad; Pessoa, H; Núñez Vergara, Luis (Elsevier, 1997)
      The electrochemical reduction of three nitrotetralone derivatives by tast and differential pulse polarography and cyclic voltammetry in a wide pH range was studied. In aqueous media, the reduction of mono- and dinitrotetralone ...