Browsing by Author "Squella Serrano, Juan"
Now showing items 41-60 of 231
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Merino, M.; Núñez Vergara, Luis; Squella Serrano, Juan (SOCIEDAD CHILENA DE QUIMICA, 2000-09)Carbon paste electrodes were modified with cytochrome c reductase enzyme. The behavior of the electrodes was characterized by cyclic voltammetry. The cytochrome c reduction was investigated both on the enzyme modified ...
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Morales Pérez, María Paulina (Universidad de Chile, 2012)Los nitrocompuestos aromáticos son compuestos de interés biológico, ampliamente utilizados como fármacos en el tratamiento de diversas enfermedades que van desde problemas arteriales (nitrendipino) hasta enfermedades ...
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Contreras Contreras, Gabriela Andrea (Universidad de Chile, 2019)Desde hace unas décadas, los nanomateriales han captado la atención de los investigadores alrededor del mundo, debido a sus diversas propiedades y aplicaciones. la mayoría de los nanomateriales utilizados están basados ...
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Gamboa, J.; Cornejo, L.; Acarapi, J.; Squella Serrano, Juan (Sociedad Chilena de Quimica, 2013)As (III) was determined by differential pulse polarography (DPP) in 1 mol L-1 HCl as supporting electrolyte. For quantification, the -0.35 V peak (versus Ag/AgCl) was chosen. The obtained detection and quantification limits ...
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Mozo, J. D.; Carbajo, J.; Sturm Schaub, Juan; Núñez Vergara, Luis; Salgado, P.; Squella Serrano, Juan (Wiley, 2012)A new, sensitive, reproducible and easy-to-use flow-injection method for determining nifuroxazide based on adsorptive stripping linear sweep voltammetry over screen-printed carbon electrodes is presented. The presented ...
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Yáñez Soto, Claudia; Núñez Vergara, Luis; Squella Serrano, Juan (WILEY-V C H VERLAG GMBH, 2002-04)Carbon paste electrodes modified with beta-cyclodextrin have been investigated for voltammetric determination of nitrendipine. The immobilization of the beta-cyclodextrin on the carbon paste leads to a modification of the ...
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Yáñez,; Núñez Vergara, Luis; Squella Serrano, Juan (2002)Carbon paste electrodes modified with β-cyclodextrin have been investigated for voltammetric determination of nitrendipine. The immobilization of the β-cyclodextrin on the carbon paste leads to a modification of the electrode ...
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Yáñez, C.; Núñez Vergara, Luis; Squella Serrano, Juan (2003)The formation of inclusion complexes of well-known 1,4-dihydropyridine calcium antagonists, such as nifedipine (NF) and nicardipine (NC), with beta-cyclodextrin (betaCD) was investigated by differential pulse polarography ...
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Squella Serrano, Juan; Borges, Y.; Bobadilla, L.; Núñez Vergara, Luis (1990)A new differential pulse polarographic method for the determination of buspirone pharmaceutical formulations is proposed. The method is based on the CN bond electroactivity of buspirone pirimidinic ring. Recovery study ...
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Álvarez Lueje, Alejandro; Pujol, Silvina; Núñez Vergara, Luis; Squella Serrano, Juan (AOAC INTERNATIONAL, 2002-11)Lercanidipine in ethanol-0.04M Britton-Robinson buffer (20 + 80) gives an irreversible anodic response on a glassy carbon electrode in a broad pH range (2-12) that depends on pH. This signal can be attributed to oxidation ...
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Núñez Vergara, Luis; Pardo Jiménez, V; Barrientos, C.; Olea Azar, Claudio; Navarrete-Encina, P. A.; Squella Serrano, Juan (2012)In this study, two series of dihydropyridine-fused and pyridine-fused coumarins were synthesised and electrochemically characterised in aprotic medium. In both series, the most easily reducible groups were the endocyclic ...
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Núñez Vergara, Luis; Yudelevich, J.; Squella Serrano, Juan; Speisky Cosoy, Hernán (Oxford University Press, 1991)Acetaldehyde, at concentrations occurring in vivo was found to avidly react in vitro with several clinically relevant drugs. The greatest reactivity was observed for the hydrazine and hydrazide-containing drugs, hydralazine ...
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Maya Arango, Juan; Morello Casté, Antonio; Repetto Scaramelli, Yolanda; Tellez Neubauer, Rowena; Rodríguez, A.; Zelada, U.; Puebla, P.; Caballero S., Esther; Medarde, M.; Núñez Vergara, Luis; Squella Serrano, Juan; Bontá, M.; Bollo Dragnic, Soledad; Feliciano M., Arturo San (PERGAMON-ELSEVIER SCIENCE, 2000-01)A series of 3-chloro-phenyl-1,4-dihydropyridine derivatives produced different degrees of inhibition of parasite growth and respiration on clone Brener, LQ and Tulahuen strains of Trypanosome cruzi epimastigotes. Respiratory ...
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Moscoso Cabello, Raúl Andrés; Inostroza Briones, Elías; Bollo Dragnic, Soledad; Squella Serrano, Juan (Springer, 2016)We report that glassy carbon electrode (GCE) modified with multiwalled carbon nanotubes (MWCNTs) can encapsulate or entrap 3,5-dinitrobenzoic acid (35DNB) generating a 35DNB-MWCNTGC electrode. After electrochemical reduction ...
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Contreras, G.; Barrientos, C; Moscoso, R.; Álvarez Lueje, Alejandro; Squella Serrano, Juan (Elsevier, 2020)In this work, we have both synthesized and studied 4-phenylbutyl-3,5-dinitrobenzoate (3,5-DNBPh) as a potential precursor of an electrocatalytic mediator for the oxidation of NADH, with the di-nitro compound immobilized ...
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Moscoso Cabello, Raúl Andrés; Barrientos, C.; Moris, S.; Squella Serrano, Juan (Elsevier B.V., 2019)In a previous study, we revealed a new way to modify multi-walled carbon nanotubes (MWCNTs) with 3,5-dinitrobenzoic acid (35DNB). Furthermore, we proved that a 35DNB-MWCNTGC electrode efficiently catalysed the oxidation ...
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Electrochemical and EPR characterization of 1,4-dihydropyridines. Reactivity towards alkyl radicals Núñez Vergara, Luis; López Alarcón, Camilo; Navarrete Encina, Patricio; Atria Salas, Ana María; Camargo Grandón, Rodrigo; Squella Serrano, Juan (TAYLOR & FRANCIS LTD, 2003)This work reports the electrochemical oxidation of a series of three synthesized 4-substituted-1,4-dihydropyridine derivatives in different electrolytic media. Also, an EPR characterization of intermediates and the reactivity ...
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Núñez Vergara, Luis; Santander Gutiérrez, Ingrid Paola; Navarrete Encina, Patricio; Valenzuela Pedevila, Jorge; Sturm Schaub, Juan; Squella Serrano, Juan (ELECTROCHEMICAL SOC, 2006)The present paper deals with the electrochemical and electron spin resonance (ESR) characterization of a number of nitroso phenyl 1,4-dihydropyridines in aprotic media on a hanging drop mercury electrode (HDME). The ...
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Núñez Vergara, Luis; Bollo Dragnic, Soledad; Fuentealba Arcos, Jorge Patricio; Sturm Schaub, Juan; Squella Serrano, Juan (KLUWER ACADEMIC/PLENUM PUBL, 2002-04)Purpose. To characterize the electrochemical behavior of the photodegradation product of nifedipine, i.e., 2,6-dimethyl-4-(2-nitrosophenyl)-3,5-pyridine-carboxylic acid dimethyl ester (NPD) in different electrolytic media. ...
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Quintana Espinoza, P.; Yáñez, C.; Escobar, C.; Sicker, D.; Araya Maturana, Ramiro; Squella Serrano, Juan (2006)Three 2′-hydroxy chalcone derivatives were electrochemically reduced to the radical anion by a reversible one-electron transfer followed by a chemical dimerization reaction. Under suitable conditions of the medium, the ...