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Evaluación preliminar de los productos de higiene industrial utilizados en el proceso de lavado de los equipos mezcladores en el área de fabricación
(Universidad de Chile, 2004)
el proceso de lavado y sanitizado de los equipos mezcladores en el área de fabricación, con la finalidad de lograr una optimización en dicho proceso.
Para tal proposito se contactó a distintos proveedores de productos de higiene industrial, de modo...
Realización de una autoinspección y actualización, desarrollo e implementación de procedimientos operativos estandarizados referentes al menejo de inventario de materias primas en el Departamento de Fabricación de una industria cosmética
(Universidad de Chile, 2006)
-Farmacéutico. Las tareas desarrolladas tuvieron lugar específicamente en el área de Fabricación, dependiente del Departamento Producción, cuyos objetivos fundamentales fueron la realización de una Autoinspección, que permitió detectar algún incumplimiento en las...
Mezclilla reciclada como materia prima para el diseño y fabricación de artículos para gatos indoor
(Universidad de Chile, 2023)
tanto a los gatos indoor como al medio ambiente.
Un aspecto clave que respalda esta propuesta es la favorable experimentación con el material, revelando su versatilidad y adaptabilidad para la fabricación de productos innovadores y atractivos.
La...
Desarrollo de un método DIY (hazlo tú mismo) que sistematice la fabricación de materiales que se cocinan a partir de hidrocoloides y residuos orgánicos : casos de estudio bagazo de té y cáscara de naranja
(Universidad de Chile, 2021)
...............................34
Capítulo 3: Metodología...................................53
4.1 Levantamiento de información sobre las etapas de fabricación de
materiales biobasados a partir de tesis chilenas.
4.2 Levantamiento de información y experimentación preliminar con...
Aplicación de metodología Dmaic para la disminución de pérdida en fabricación chocolate de una planta productora de chocolates
(Universidad de Chile, 2019)
de Nestlé Chile tuvo una pérdida 2,89% en el sector Fabricación de Chocolate equivalente a $539.562.000 de CLP, aportando con el 33% del total de pérdidas de la Planta de Chocolates. El alto nivel de pérdida se debe a que en esta línea se utilizan...
This present project was developed in the Nestle Chile’s chocolate factory, located in Santiago de Chile, Maipú, from January to July 2018. In 2017, Nestle Chile’s chocolate Factory had a waste of 2,89% in the chocolate manufacturing section, which equals to $539.562.000 of CLP, or 33% of the total waste of the whole chocolate factory. This amount of loss is due to the high pricing and volume of consumption of raw materials used by these lines of production, because these semi-finished products supply the whole factory of chocolate, cookies and ice cream. It is proposed to implement a continuous improvement strategy, based on the DMAIC methodology (define, measure, analyze, improve, control) to decrease the waste of material during the manufacturing of chocolate and compound of the chocolate factory production line of semi-finished products, with the objective of reducing them in 30%. Following the DMAIC methodology, a multidisciplinary team was created, the potential causes of loss in each fabrication step were identified and people responsible were assigned for its implementation. The capacity of this process was measured using statistic tools. Initially, the capacity of this process had a value of Cp = 0,52 and Cpk = -0,41, which increased to 6,07 and 2,36 respectively after the implementation of the potential improvements identified. Finally, after the implementation of the DMAIC method, we achieved even better results than expected, decreasing the loss in 68,8%. It was concluded that the DMAIC methodology was effective in decreasing the waste in the lines of production, therefore it was found that it is recommended to extrapolate this strategy to other problems in the production plants...
This present project was developed in the Nestle Chile’s chocolate factory, located in Santiago de Chile, Maipú, from January to July 2018. In 2017, Nestle Chile’s chocolate Factory had a waste of 2,89% in the chocolate manufacturing section, which equals to $539.562.000 of CLP, or 33% of the total waste of the whole chocolate factory. This amount of loss is due to the high pricing and volume of consumption of raw materials used by these lines of production, because these semi-finished products supply the whole factory of chocolate, cookies and ice cream. It is proposed to implement a continuous improvement strategy, based on the DMAIC methodology (define, measure, analyze, improve, control) to decrease the waste of material during the manufacturing of chocolate and compound of the chocolate factory production line of semi-finished products, with the objective of reducing them in 30%. Following the DMAIC methodology, a multidisciplinary team was created, the potential causes of loss in each fabrication step were identified and people responsible were assigned for its implementation. The capacity of this process was measured using statistic tools. Initially, the capacity of this process had a value of Cp = 0,52 and Cpk = -0,41, which increased to 6,07 and 2,36 respectively after the implementation of the potential improvements identified. Finally, after the implementation of the DMAIC method, we achieved even better results than expected, decreasing the loss in 68,8%. It was concluded that the DMAIC methodology was effective in decreasing the waste in the lines of production, therefore it was found that it is recommended to extrapolate this strategy to other problems in the production plants...
Disminución de la variabilidad y los tiempos de fabricación por medio de la metodología Lean Six Sigma en una industria
(Universidad de Chile, 2020)
costo-competitivos.
En la industria farmacéutica ocurren múltiples procesos de fabricación en serie y en paralelo, la ventaja de trabajar de este modo es que se puede lograr una gran eficiencia. Sin embargo, es sumamente complejo adaptar las líneas a...
In the last decades many productive plants of transnational pharmaceutical laboratories have been closed to establish themselves in other countries for their economic and productive advantages, to then export their products to our country, also, the national producing laboratories must compete with the medicines coming from China and India, which have much lower operating and production costs, is how operational excellence becomes essential to be cost-competitive. In the pharmaceutical industry there are multiple manufacturing processes in series and in parallel, the advantage of working in this way is that great efficiency can be achieved, however it is extremely complex to adapt the lines to different processes (from a product A to a product B) and these must be properly balanced, for this it is essential to have all the standardized times and have a certain planning, every time the process times are not met or their capacity is underestimated, bottlenecks are generated that increase manufacturing costs and times incorporating inefficiency and variability to the operation. The objective of this work was to reduce variability and manufacturing times, specifically in compression, using the Lean Six Sigma methodology. Work was done using the DMAIC cycle and the data was analyzed with Minitab statistical software detecting the bottlenecks, minimizing downtime, based on the findings, the work standard used until then was created and / or improved, streamlining the flow of processes and properly planning the sequence of manufacturing orders. After the implementation of the various improvements, around 1500 hours of annualized machines were released in the solid-manufacturing core, which allowed to increase the volume of manufacturing, improve the workflow and give greater flexibility to the production plant...
In the last decades many productive plants of transnational pharmaceutical laboratories have been closed to establish themselves in other countries for their economic and productive advantages, to then export their products to our country, also, the national producing laboratories must compete with the medicines coming from China and India, which have much lower operating and production costs, is how operational excellence becomes essential to be cost-competitive. In the pharmaceutical industry there are multiple manufacturing processes in series and in parallel, the advantage of working in this way is that great efficiency can be achieved, however it is extremely complex to adapt the lines to different processes (from a product A to a product B) and these must be properly balanced, for this it is essential to have all the standardized times and have a certain planning, every time the process times are not met or their capacity is underestimated, bottlenecks are generated that increase manufacturing costs and times incorporating inefficiency and variability to the operation. The objective of this work was to reduce variability and manufacturing times, specifically in compression, using the Lean Six Sigma methodology. Work was done using the DMAIC cycle and the data was analyzed with Minitab statistical software detecting the bottlenecks, minimizing downtime, based on the findings, the work standard used until then was created and / or improved, streamlining the flow of processes and properly planning the sequence of manufacturing orders. After the implementation of the various improvements, around 1500 hours of annualized machines were released in the solid-manufacturing core, which allowed to increase the volume of manufacturing, improve the workflow and give greater flexibility to the production plant...
Rediseño del Proceso Administrativo para la Fabricación de Persianas y Cortinas en la Empresa Hunter Douglas Chile S.A
(Universidad de Chile, 2007)
Hunter Douglas Chile S.A. es una empresa mediana dedicada a la fabricación de
persianas y cortinas, las cuales comercializa a través de sus marcas Luxaflex y Flexalum.
En la actualidad, es líder indiscutido de su industria y sus productos son...
Reestructuración y rediseño de un área de fabricación en un laboratorio farmacéutico
(Universidad de Chile, 2016)
El trabajo de tesis se enfoca en la reestructuración y rediseño de un área de fabricación de un laboratorio farmacéutico para cumplir los requerimientos de las Buenas Prácticas de Manufactura. Toma como punto de inicio un informe emitido por las...
The work developed for this thesis, has an approach in restructuring and redesign of a manufacturing area in a Pharmaceutical Manufacturing Laboratory, in order to fulfill the requirements of the Good Manufacturing Practices (GMP), taking as starting line a report issued by Regulatory Auditors from Agencia Nacional de Medicamentos del Instituto de Salud Pública de Chile, in which is stated that the manufacturing area of liquid and semisolid dosage forms is not in compliance with the GMP requirements. It is approached from the perspectives of the Quality Assurance and Production departments, which, according to World Health Organization Technical reports, and local regulations, are the departments in charge of assure the compliance of Good Manufacturing Practices inside of a Manufacturing site. This dual look of quality and productivity should go together to achieve greater results in order to deliver products with quality, safe and effective. The methodology used for this thesis, corresponds in first place to reviews of the modifications required for Regulatory compliance, with the suitable consultant to World Health Organization Technical reports, to local regulations and applicable bibliography regarding the manufacturing of pharmaceuticals products. As second stage, an inspection of the restructuring work and changes in order to verify the compliance of the items regarding good manufacturing practices, including flows and processes associated, with the objective of fulfill the requirements requested, that in a late stage will be submitted to the approval of the Agencia Nacional de Medicamentos del Instituto de Salud Pública de Chile. In a third step, changes are made in the processes and procedures to have an adequate flow design. These changes lead to an update of the standards operating procedures, part of the Documental Quality Management System, with its corresponding distribution and training of personnel involved for normal operation of the area. In a fourth stage, tests of manufacturing area classification area made, where are measured the particulate concentration in the filling rooms and in packaging rooms of liquid and semisolid dosage forms, to evaluate the fulfilling with the requirements of GMP. Finally, the impact on productivity of manufactured units in the improved areas and improved processes is evaluated, comparing the pre-change and post-change half semester historical data. With the compliance of all the stages, is achieved the implementation of an area that meets the request of the regulatory authority in conformance with the requirements of good manufacturing practices, along with an improvement of the productivity of the manufacturing area...
The work developed for this thesis, has an approach in restructuring and redesign of a manufacturing area in a Pharmaceutical Manufacturing Laboratory, in order to fulfill the requirements of the Good Manufacturing Practices (GMP), taking as starting line a report issued by Regulatory Auditors from Agencia Nacional de Medicamentos del Instituto de Salud Pública de Chile, in which is stated that the manufacturing area of liquid and semisolid dosage forms is not in compliance with the GMP requirements. It is approached from the perspectives of the Quality Assurance and Production departments, which, according to World Health Organization Technical reports, and local regulations, are the departments in charge of assure the compliance of Good Manufacturing Practices inside of a Manufacturing site. This dual look of quality and productivity should go together to achieve greater results in order to deliver products with quality, safe and effective. The methodology used for this thesis, corresponds in first place to reviews of the modifications required for Regulatory compliance, with the suitable consultant to World Health Organization Technical reports, to local regulations and applicable bibliography regarding the manufacturing of pharmaceuticals products. As second stage, an inspection of the restructuring work and changes in order to verify the compliance of the items regarding good manufacturing practices, including flows and processes associated, with the objective of fulfill the requirements requested, that in a late stage will be submitted to the approval of the Agencia Nacional de Medicamentos del Instituto de Salud Pública de Chile. In a third step, changes are made in the processes and procedures to have an adequate flow design. These changes lead to an update of the standards operating procedures, part of the Documental Quality Management System, with its corresponding distribution and training of personnel involved for normal operation of the area. In a fourth stage, tests of manufacturing area classification area made, where are measured the particulate concentration in the filling rooms and in packaging rooms of liquid and semisolid dosage forms, to evaluate the fulfilling with the requirements of GMP. Finally, the impact on productivity of manufactured units in the improved areas and improved processes is evaluated, comparing the pre-change and post-change half semester historical data. With the compliance of all the stages, is achieved the implementation of an area that meets the request of the regulatory authority in conformance with the requirements of good manufacturing practices, along with an improvement of the productivity of the manufacturing area...
Diseño de una estrategia para una empresa de fabricación y comercialización de cortinas roller
(Universidad de Chile, 2016)
TopRoller, empresa dedicada a la fabricación y comercialización de cortinas roller, fue fundada el año 2013. Tuvo un gran crecimiento entre el 2014 y 2015 (330%), pasando de 300 a 1.000 millones de pesos en sus ingresos. Su propuesta de valor está...
"Plan de negocios para la expansión de un taller de fabricación de carpas"
(Universidad de Chile, 2021)
El objetivo de este trabajo de título es realizar un plan de negocios para la expansión del taller de fabricación de carpas y cubiertas, Carpas Rayen. El principal problema que motiva este trabajo es el bajo rendimiento de ventas de la empresa, que...