Now showing items 5678-5697 of 8181

    • Zambrano, Cristian; Egaña, José T; Núñez González, Marco; Maccioni Baraona, Ricardo; González Billault, Christian (PERGAMON-ELSEVIER SCIENCE LTD, 2004-06-01)
      Oxidative stress has been demonstrated to produce modifications in several intracellular proteins that lead to alterations in their activities. Alzheimer's disease is related to an increase of oxidative stress markers, ...
    • Zambrano, Cristian A.; Egaña, José T.; Núñez González, Marco; Maccioni Baraona, Ricardo; González Billault, Christian (2004)
      Oxidative stress has been demonstrated to produce modifications in several intracellular proteins that lead to alterations in their activities. Alzheimer's disease is related to an increase of oxidative stress markers, ...
    • Aliaga, Christian; Cerón-Neculpán, Masiel; Saitz Barría, Claudio; Jullian Matthaei, Carolina; Sobarzo Sánchez, Eduardo; De la Fuente, Julio (2011)
      During the 1H NMR study of the photoreduction of aza-oxoisoaporphines, aza-OIAs, (7H-benzo[e]perimidin-7-ones) by amines we found an unexpected H/D isotopic exchange in the aromatic positions 4 and 6 of these molecules. ...
    • Seguel, Rodrigo J.; Morales Segura, Raúl; Leiva Guzmán, Manuel (Elsevier Ltd., 2011-10-12)
      The study examined weekdayeweekend differences in ozone, NOx (NO and NO2) and VOC concentrations in Santiago, Chile, from 1999 to 2007. The results provide evidence for the occurrence of an atmospheric phenomenon that ...
    • Toro A., Richard; Seguel, Rodrigo J.; Morales Segura, Raúl; Leiva Guzmán, Manuel (Springer, 2015)
      The relationships between ozone (O-3) and its precursors, nitrogen oxides (NO (x) ) and volatile organic compounds (VOCs), were investigated in the VIR region (34A degrees 10' S, 71A degrees 36' W), referred to as Libertador ...
    • Cassis Abutom, Beatriz (Universidad de Chile., 1982)
      Nuestro objetivo es describir las órbitas bajo la representación Co-adjunta de los grupos de Lie G = SL (3, R), para obtener información sobre los grupos fundamentales de las órbitas de dimensión menor o igual a 4, las ...
    • Uribe Arias, Alejandro; Posada Duque, Rafael Andres; González Billault, Christian; Villegas, Andrés; Lopera, Francisco; Cardona Gómez, Gloria Patricia (Wiley-Blackwell, 2016)
      Cyclin-dependent kinase 5 (CDK5) plays important roles in synaptic function. Its unregulated over-activation has been, however, associated with neurodegeneration in Alzheimer's disease. Our previous studies revealed that ...
    • Rivas Yáñez, Elizabeth; Barrera Ávalos, Carlos; Parra Tello, Brian; Briceño, Pedro F.; Rosemblatt, Mariana V.; Saavedra Almarza, Juan Pablo; Rosemblatt Silber, Mario; Acuña Castillo, Claudio; Bono Merino, María Rosa; Sauma Mahaluf, Daniela (MDPI, 2020)
      The P2X7 receptor is a ligand-gated, cation-selective channel whose main physiological ligand is ATP. P2X7 receptor activation may also be triggered by ARTC2.2-dependent ADP ribosylation in the presence of extracellular ...
    • Posada Duque, Rafael; López Tobon, Alejandro; Piedrahita, Diego; González Billault, Christian; Cardona Gómez, Gloria (Wiley & Sons, 2015)
      CDK5 plays an important role in neurotransmission and synaptic plasticity in the normal function of the adult brain, and dysregulation can lead to Tau hyperphosphorylation and cognitive impairment. In a previous study, we ...
    • Molina Reyes, Emiliano; Cataldo, Vicente F.; Eggers, Cristián; Muñoz Madrid, Valentina Elisa; Glavic Maurer, Alvaro Alberto (Frontiers Media, 2022)
      Cells extend membrane protrusions like lamellipodia and filopodia from the leading edge to sense, to move and to form new contacts. The Arp2/3 complex sustains lamellipodia formation, and in conjunction with the actomyosin ...
    • Carvajal Landinez, Francy Milena (Universisdad de Chile, 2013)
      En este trabajo se presenta el primer estudio paleontológico y paleoclimatico detalles de la formación Ligorio Marquez (46° 45 S; 71° 50 W) Ligorio Marquez corresponde a una sucesión de areniscas y limolitas de origen ...
    • Maldonado, Antonio; Villagrán, Carolina (2002)
      Pollen analysis of two sediment records from a coastal swamp forest site in the Chilean semiarid region (31°50′S; 71°28′W) shows an alternation of dry and wet phases during the past ∼6100 cal yr B.P. The most prominent ...
    • Halac, S.; Mengo, L.; Guerra, Lucía; Lami, A.; Musazzi, S.; Loizeau, J. L.; Ariztegui, D.; Piovano, E.L. (Elsevier, 2020)
      Reservoirs hold a detailed record of the changes in the input of sediments and nutrients over decades to centuries. Paleolimnological multi-proxy analysis makes it possible to reconstruct baseline conditions to infer early ...
    • Kaffman Barba, María José (Universidad de Chile, 2019)
      La aceleración del cambio climático ha aumentado el interés en los estudios paleoambientales con el objeto de conocer la variabilidad natural del clima y sus efectos sobre el medio ambiente. En el sur de Chile estos estudios ...
    • Davis, Sergio; Loyola, Claudia; González, Felipe; Peralta, Joaquín (ELSEVIER SCIENCE BV, 2010-08-25)
      Las Palmeras Molecular Dynamics (LPMD) is a highly modular and extensible molecular dynamics (MD) code using interatomic potential functions. LPMD is able to perform equilibrium MD simulations of bulk crystalline solids, ...
    • Orellana, Carlos; Mendizábal Emaldía, Fernando; González Moraga, Guillermo; Miranda Rojas, Sebastián; Barrientos Poblete, Lorena (Elsevier B.V., 2017)
      © 2017 Elsevier B.V.A complete theoretical characterization of the factors involved in the stabilization of hybrid laminar composites is reported, with the purpose of understanding the main interactions involved in the ...
    • Manríquez Castro, Víctor; Quintana, R.; Muñoz Muñoz, Orlando; Castillo, M. (MUNKSGAARD INT PUBL LTD, 1988-01-15)
      CIsH3oBrNO3, Mr=388.3, triclinic, P1, a=7-999(2), b=15-549(7), c=7-929(2)A, a= 103.52 (3), fl= 105.57 (2), ),=86.89 (3) ° , V= 923.7 (6)/k 3, Z = 2, D x = 1.396 g cm -3, 2(Mo K0t) = 0.71069/~, g=22.15cm -l, F(000)=408, ...
    • Hörmann Cornejo, Pilar Leonor (Universidad de Chile, 2022)
      Los linfocitos T son células especializadas del sistema inmune que sufren procesos de diferenciación y selección en el timo antes de salir a la circulación. En este proceso de diferenciación, los precursores de las células ...
    • Canovas Schalchli, Jose Alfonso (Universisdad de Chile, 2014)
      La corteza cerebral es la región del cerebro responsable de nuestra habilidades cognitivas superiores, ayudándonos no solo a percibir el mundo y responder a este, sino que también a entenderlo. El asombroso poder de ...
    • Espejo Trujillo, Pablo David (Universidad de Chile, 2009)
      Las células dendríticas (DCs) cumplen un papel central en el desarrollo de la respuesta inmune puesto que son capaces de iniciar y dirigir la respuesta adaptativa hacia un tipo de respuesta tipo Th1 o Th2. Esto ocurre ...