Now showing items 1361-1380 of 4844

    • Pinto Fernández, Nazaret Nahazar (Universidad de Chile, 2015)
      Práctica prolongada desarrollada en el departamento de Operaciones Analíticas (que involucra áreas de Control de Calidad, Estabilidad y Validaciones) de Laboratorios Synthon Chile Ltda., para optar a el título de Químico ...
    • Parraguez Pávez, Rodrigo Antonio (Universidad de Chile, 2013)
      La empresa farmacéutica Laboratorios Saval S.A., al momento de la realización del siguiente trabajo, se encontraba en un proceso de mejoras e implementación de un plan de actualización de toda la documentación utilizada ...
    • Heredia Moya, Jorge; Krohn, Karsten; Florke, Ulrich; Pessoa Mahana, Hernán; Weiss López, Boris; Estévez, A.; Araya Maturana, Ramiro (PERGAMON-ELSEVIER SCIENCE LTD, 2007-06-01)
      E)-Ethyl 3-(4-oxo-4H-chromen-3-yi)acrylate (3), (E)-3-(4-oxo-4H-chromen-3-yl)-2-propenenitrile (12) and their 5-hydroxy-derivatives 11 and 13 undergo alternative, solvent dependent, domino reactions with ethyl vinyl ether. ...
    • Saller, Sabine; Kunz, L.; Berg, D.; Berg, U.; Lara Peñaloza, Hernán; Urra, J.; Hecht, S.; Pavlik, R.; Thaler, C.J.; Mayerhofer, A. (Oxford University Press, 2014)
      studyquestion: Is the neurotransmitter dopamine (DA) in the human ovary involved in the generation of reactive oxygen species (ROS)? summary answer: Human ovarian follicular fluid contains DA, which causes the generation ...
    • Paris Pizarro, Irmgard; Martínez Alvarado, P.; Cárdenas, S.; Pérez Pastene, C.; Graumann, Rebecca; Fuentes, P.; Olea Azar, Claudio; Caviedes Fernández, Pablo; Segura Aguilar, Juan (AMER CHEMICAL SOC, 2005-03)
      We report a new and specific mechanism for iron-mediated neurotoxicity using RCHT cells, which were derived from rat hypothalamus. RCHT cells exhibit immunofluorescent-positive markers for dopamine beta-hydroxylase and the ...
    • Israel Jacard, Yedy; Crabbe, John C.; Harris, R. Adron (WILEY-BLACKWELL, 2012)
    • Oyarzún Araya, Macarena del Pilar (Universidad de ChilePrograma Cybertesis, 2007)
    • Silva, Wladimir; Torres Gatica, María Fernanda; Oyarzún Ampuero, Felipe; Silva Weiss, Andrea; Robert Canales, Paz; Cofrades, Susana; Giménez, Begoña (Elsevier, 2018)
      The development of fat replacers to obtain healthier/functional foods is a constant challenge. With this aim, double emulsions (DE) with a blend of olive, linseed and fish oils as oil phase were developed. To prevent the ...
    • Robert Canales, Paz; Zamorano, Marcela; Prado González, Estefanía; Silva-Weiss, Andrea; Cofrades, Susana; Giménez, Begoña (Elsevier Ltd, 2019)
      Double emulsions (DE) with a healthy oil blend as lipid phase and an olive leave extract (OLE) encapsulated in the internal aqueous phase (DE/OLE) were incorporated as fat replacers in meat systems, in order to improve ...
    • Gómez, Wileidy; Morales, Rodrigo; Maracaja Coutinho, Vinicius; Parra Ortiz, Valentina; Nassif, Melissa (Impact Journals LLC, 2020)
      Alzheimer’s disease (AD) is the most prevalent type of dementia. Down syndrome (DS) is the leading genetic risk factor for Early-Onset AD, prematurely presenting the classic pathological features of the brain with AD. ...
    • Parra Ortíz, María Valentina; Altamirano, Francisco; Hernández Fuentes, Carolina; Tong, Dan; Kyrychenko, Victoriia; Rotter, David; Pedrozo Cibils, Zully; Hill, Joseph A.; Eisner, Verónica; Lavandero González, Sergio; Schneider, Jay W.; Rothermel, Beverly A. (Lippincott Williams & Wilkins, 2018)
      Rationale: The regulator of calcineurin 1 (RCAN1) inhibits CN (calcineurin), a Ca2+-activated protein phosphatase important in cardiac remodeling. In humans, RCAN1 is located on chromosome 21 in proximity to the Down ...
    • Letelier Muñoz, María Eugenia; Molina Berríos, Alfredo Enrique; Cortés Troncoso, Juan; Jara Sandoval, José; Holst, Marianne; Palma, Karina; Montoya, Margarita; Miranda, Dante; González Lira, Víctor (PERGAMON-ELSEVIER SCIENCE LTD, 2008-03)
      Numerous investigations exist about the alterations that oxygen free radicals can provoke on biomolecules; these modifications can be prevented and/or reversed by different antioxidants agents. On the other hand, ...
    • Cortés, Manuel; Delgado, Virginia; Saitz Barría, Claudio; Armstrong, Verónica (2011)
      Several reviews have been published on sesquiterpenes, and on drimane-type sesquiterpenes, going through drimenol and related compounds among others. However, to our knowledge, this is the first review exclusively on ...
    • Chou, Wai-Houng; Galaz, Ariel; Jara, Miguel O.; Gamboa, Alexander; Morales Montecinos, Javier (MDPI, 2020)
      The aim of the study was to develop a novel buccal dosage form to transport rhodamine 123 and human insulin as models for poorly water-soluble and biological drugs, using lipid-core micelles (LCMs)-loaded mucoadhesive ...
    • Fungo, Marta Stella Maris; Vega, Elena María (Sociedad Argentina de Pediatria, 2013)
      Introduction: The objective was to analyze the number of drugs dispensed by the Pharmacy Department to the Neonatology Division, to find out if the use of these drugs is described on the package insert approved by the ...
    • Báez Guerrero, Hernán; Camargo Grandón, Rodrigo; Benavente, M. A.; Kintz, P.; Castro Domínguez, Mario; Cirimele, V.; Thomas, C. (ELSEVIER SCI IRELAND LTD, 2000-02-28)
      Concern about drug abuse in modem populations has led to the development of specific methods for identification of cocaine, opiates and cannabis in human hair. Drug use in prehistory can provide indirect evidence of ...
    • Cárdenas Muñoz, Sergio Patricio (Universidad de ChilePrograma Cybertesis, 2008)
    • Pizarro, Nancy; Duque, Mario; Chamorro, Eduardo; Nonell, Santi; Manzur Saffie, Jorge; De la Fuente, Julio; Günther Sapunar, Germán; Cepeda Plaza, Marjorie; Vega, Andrés (American Chemical Society, 2015)
      © 2015 American Chemical Society. The spectroscopic, electrochemical, and photophysical properties of the new complex [P,N-{(C<inf>6</inf>H<inf>5</inf>)<inf>2</inf>(C<inf>5</i ...
    • Pizarro, Nancy; Duque, Mario; Chamorro, Eduardo; Nonell, Santi; Manzur Saffie, Jorge; Fuente Urrutia, Julio de la; Günther Sapunar, Germán; Cepeda Plaza, Marjorie; Vega, Andrés (American Chemical Society, 2015)
      The spectroscopic, electrochemical, and photophysical properties of the new complex [P,N-{(C6H5)(2)(C5H4N)-P}Re(CO)(3)Br] are reported. The UV-vis spectrum in dichloromethane shows an absorption maximum centered at 315 rim ...
    • Gunther,; Morgado, (1996)
      The aim of the present study was to differentiate two modalities of intrinsic time scales : i- the geometric or Euclidean modality, which is based on the constant speed of mass transport or of wave transmission in cylindrical ...