Now showing items 1-11 of 11

    • Silva Valenzuela, Cecilia; Molina Quiroz, Roberto; Desai, Prerak; Valenzuela, Camila; Porwollik, Steffen; Zhao, Ming; Hoffman, Robert M.; Andrews-Polymenis, Helene; Contreras, Inés; Santiviago Cid, Carlos; McClelland, Michael (Frontiers Media, 2016)
      Two pools of individual single gene deletion (SOD) mutants of S. Typhimurium 14028s encompassing deletions of 3,923 annotated non-essential ORFs and sRNAs were screened by intraperitoneal (IP) injection in BALB/c mice ...
    • Zabner Espinoza, Marcela Estefanía (Universidad de Chile, 2022)
      Salmonella es un género de bacterias Gram negativo que incluye más de 2500 serovares, los cuales se distinguen por los antígenos presentes en su superficie. Los serovares de S. enterica subespecie enterica son causantes ...
    • Espinoza, Rodrigo A.; Silva Valenzuela, Cecilia A.; Amaya, Fernando A.; Urrutia, ítalo M.; Contreras, Inés; Santiviago, Carlos A. (BioMed Central, 2017)
      Background: Salmonella pathogenicity island (SPI)-13 is conserved in many serovars of S. enterica, including S. Enteritidis, S. Typhimurium and S. Gallinarum. However, it is absent in typhoid serovars such as S. Typhi and ...
    • Molina Quiroz, Roberto C.; Silva, Cecilia A.; Molina, Cristian F.; Leiva, Lorenzo E.; Reyes Cerpa, Sebastián; Contreras, Inés; Santiviago Cid, Carlos (Royal Soc., 2015)
      It has been proposed that sub-inhibitory concentrations of antibiotics play a role in virulence modulation. In this study, we evaluated the ability of Salmonella enterica serovar Typhimurium (hereafter S. Typhimurium) to ...
    • Fernández, Paulina; Velásquez, Felipe; Garcias-Papayani, Héctor; Amaya, Fernando; Ortega, Jaime; Gómez, Sebastian; Santiviago Cid, Carlos; Álvarez, Sergio A. (Frontiers Media SA., 2018-06)
      Lipid A is the bioactive component of lipopolysaccharide, and presents a dynamic structure that undergoes modifications in response to environmental signals. Many of these structural modifications influence Salmonella ...
    • Ortega, A.; Villagra, N.; Urrutia, Isabel M.; Valenzuela, L.; Talamilla Espinoza, A.; Hidalgo, A.; Rodas, P.; Gil, F.; Calderón, I.; Paredes Sabja, D.; Mora, G.; Fuentes, J. (Elsevier, 2016)
      The difference in host range between Salmonella enterica serovar Typhimurium(S. Typhimurium) and Salmonella enterica serovar Typhi (S. Typhi) can be partially attributed to the gain of functions, to the loss of functions ...
    • Fernández Oyarzún, Paulina Alejandra; Zabner Espinoza, Marcela Estefanía; Ortega Berríos, Jaime Ignacio; Morgado Ruiz, Constanza Patricia; Amaya Inzunza, Fernando Andrés; Vera Sánchez, Gabriel Alberto; Rubilar Leyton, Carolina Andrea; Salas Valenzuela, Beatriz Elizabeth; Cuevas, Víctor; Valenzuela Montenegro, Camila; Baisón Olmo, Fernando; Álvarez Armijo, Sergio Aníbal; Santiviago Cid, Carlos Alberto (MDPI, 2021)
      The type III secretion systems (T3SS) encoded in pathogenicity islands SPI-1 and SPI-2 are key virulence factors of Salmonella. These systems translocate proteins known as effectors into eukaryotic cells during infection. ...
    • Silva Valenzuela, Cecilia; Velásquez, Felipe; Peñailillo, Johany; Garcías Papayani, H éctor; Fernández, Paulina; Tobar, Pía; Contreras, Inés; Santiviago Cid, Carlos; Álvarez Armijo, Sergio (Elsevier, 2016)
      Lipopolysaccharide (LPS) consists of three covalently linked domains: the lipid A, the core region and the O antigen (OAg), consisting of repeats of an oligosaccharide. Salmonella enterica serovar Enteritidis (S. Enteritidis) ...
    • Riquelme, Sebastián; Varas, Macarena; Valenzuela, Camila; Velozo Hermosilla, Paula Elizabeth; Chahin, Nicolás; Aguilera, Paulina; Sabag, Andrea; Labra, Bayron; Álvarez Armijo, Sergio; Chávez, Francisco P.; Santiviago Cid, Carlos (Frontiers Media, 2016)
      The social amoeba Dictyostelium discoideum has proven to be a useful model for studying relevant aspects of the host-pathogen interaction. In this work, D. discoideum was used as a model to study the ability of Salmonella ...
    • Valenzuela, Camila; Gil, Magdalena; Urrutia, Ítalo M.; Sabag, Andrea; Enninga, Jost; Santiviago Cid, Carlos (Wiley, 2021)
      The ability ofSalmonellato survive and replicate within mammalian host cells involves the generation of a membranous compartment known as theSalmonella-containing vacuole (SCV).Salmonellaemploys a number of effector proteins ...
    • Araujo Garrido, Juan Luis; Baisón Olmo, Fernando; Bernal Bayard, Joaquín; Romero, Francisco; Ramos Morales, Francisco (MDPI, 2020)
      Salmonella enterica serovar Typhimurium is a human and animal pathogen that uses type III secretion system effectors to manipulate the host cell and fulfill infection. SseK1 is a Salmonella effector with glycosyltransferase ...