Now showing items 1781-1800 of 2558

    • González Bergas, Fermín; Ramírez Fernández, Marcos; Allerbring, Eva B.; Fasching, Nina; Lundqvist, Andreas; Poschkee, Isabel; Achour, Adnane; Salazar Onfray, Flavio (Elsevier, 2013-10-12)
      Background: Melanocortin 1 Receptor (MC1R) is expressed in a majority of melanoma biopsies and cell lines. We previously demonstrated that three hydrophobic low-affinity HLA-A2-restricted MC1R-derived peptides: MC1R291–298, ...
    • González Bergas, Fermín; Ortiz, Carolina; Reyes Rojas, Montserrat; Dutzan Muñoz, Nicolás; Patel, Vyomesh; Pereda, Cristián; Gleisner Muñoz, María Alejandra; López Nitsche, Mercedes; Gutkind, J. Silvio; Salazar Onfray, Flavio (John Wiley & Sons Ltd,, 2014)
      We have previously reported a novel method for the production of tumour-antigen-presenting cells (referred to as TAPCells) that are currently being used in cancer therapy, using an allogeneic melanomaderived cell lysate ...
    • Lopez, N.; Lobos, N. (1976)
      A case of metastatic neoplasm developing in the gingiva from a primary lesion, probably sited in the gastric mucosa, has been reported. In this case, the first demonstrable metastatic lesion was located in the gingiva. The ...
    • Jara, J. A.; López Muñoz, R. (Elsevier, 2015)
      For decades, metformin has been the first-line drug for the treatment of type II diabetes mellitus, and it thus is the most widely prescribed antihyperglycemic drug. Retrospective studies associate the use of metformin ...
    • Wu, Darong; Akl, Elie A.; Guyatt, Gordon H.; Devereaux, Philip J.; Brignardello Petersen, Romina; Prediger, Barbara; Patel, Krupesh; Patel, Namrata; Lu, Taoying; Zhang, Yuan; Falavigna, Maicon; Santesso, Nancy; Mustafa, Reem A.; Zhou, Qi; Briel, Matthias; Schünemann, Holger J. (BioMed Central Ltd., 2014)
      Background: Although even randomization (that is, approximately 1:1 randomization ratio in study arms) provides the greatest statistical power, designed uneven randomization (DUR), (for example, 1:2 or 1:3) is used to ...
    • Kretschmar, Catalina; Hernández Cáceres, María Paz; Reyes Rojas, Montserrat; Peña Oyarzún, Daniel; García Navarrete, Camila; Troncoso Cotal, Rodrigo Hernán; Díaz Castro, Francisco; Budini Budini, Mauricio Fernando; Morselli, Eugenia; Riquelme Meléndez, Jaime Andrés; Hill, Joseph A.; Lavandero González, Sergio; Criollo Céspedes, Alfredo (Elsevier, 2023)
      Cardiovascular diseases are the leading cause of death and disability worldwide. After heart injury triggered by myocardial ischemia or myocardial infarction, extensive zones of tissue are damaged and some of the tissue ...
    • Ciudad Pérez, Soledad Andrea del Carmen (Universidad de Chile, 2023)
      El carcinoma oral de células escamosas es un problema de salud pública para Chile y corresponde al 90% de neoplasias de la cavidad oral. En este contexto, surge el interés por investigar terapias adyuvantes a los ...
    • Pacheco Parada, María José (Universidad de Chile, 2022)
      Introducción: La evaluación de las maloclusiones es fundamental para el establecimiento de un diagnóstico y la determinación de las necesidades de tratamiento de los pacientes. Los índices ortodónticos permiten evaluar ...
    • Sierra Cristancho, Alfredo José; González Osuna, Luis; Poblete, Daniela; Cafferata Chea, Emilio Alfredo; Carvajal Pavez, Paola Lorena; Lozano Moraga, Carla Paola; Vernal Astudillo, Rolando Marcelo (Nature, 2021)
      This study aimed to analyze the root anatomy and root canal system morphology of mandibular first premolars in a Chilean population. 186 teeth were scanned using micro-computed tomography and reconstructed three-dimensionally. ...
    • Mejías Becerra, Nicolás (Universidad de Chile, 2023)
      INTRODUCCIÓN: El sistema musculoesquelético presenta una alta coordinación entre sus tejidos componentes, por lo que la alteración de una de sus partes puede desencadenar efectos en todo este sistema. La parálisis ...
    • Leiva Büchi, Marisol Beatriz (Universidad de Chile, 2007)
      Se midió experimentalmente in vitro la microfiltración alcanzada en 80 incrustaciones de resina compuesta cementadas con resina fluida utilizando un sistema autograbante (Go!, SDI, Australia) versus un sistema de ...
    • Rojas Torres, Paula Andrea (Universidad de Chile, 2010)
      Se realizó un estudio comparativo in vitro propuesto por el área de Biomateriales odontológicos, para evaluar el grado de sellado marginal de restauraciones indirectas de resina compuesta cementadas con cementos con ...
    • Venegas Hermosilla, Juan; Díaz Cuevas, Laín; Rojas, Tamara; Miranda, Sandra; Jercic, M. I.; González, Christian; Coñoepán, William; Vargas, Álex; Pichuantes, Sergio; Gajardo Ramírez, Marta Kelly; Rodríguez Borges, Jorge; Sánchez, Gittith (Stefan´ski Institute of Parasitology, 2013)
      The objective of this study was to investigate if there is specific host-parasite association in Chilean populations of Trypanosoma cruzi. For this purpose, two groups of parasites were analyzed, one from chronic chagasic ...
    • Martin, J.; Fernandez, E.; Estay, J.; Gordan, V.; Mjor, I.; Moncada, G. (2013)
      Replacement of dental restorations has been the traditional treatment for restorations that are defective. In this five-year randomized clinical trial, restorations with localized marginal defects were treated with ...
    • Johnston, Bradley C.; Ebrahim, Shanil; Carrasco Labra, Alonso; Furukawa, Toshi A.; Patrick, Donald L.; Crawford, Mark W.; Hemmelgarn, Brenda R.; Schunemann, Holger J.; Guyatt, Gordon H.; Nesrallah, Gihad (BMJ Publishing Group, 2015)
      Introduction Patient-reported outcomes (PROs) are often the outcomes of greatest importance to patients. The minimally important difference (MID) provides a measure of the smallest change in the PRO that patients perceive ...
    • Strauss Avendaño, Franz; Stahli, Alexandra; Kobatake, Reiko; Tangl, Stefan; Heimel, Patrick; Alccayhuaman, Karol Ali Apaza; Schosserer, Markus; Hackl, Matthias; Grillari, Johannes; Gruber, Reinhard (Wiley, 2020)
      Objectives MicroRNAs (miRNAs) are small noncoding RNAs demonstrated as critical post-transcriptional modulators in dental tissues and bone regeneration, particularly miR-21-5p. However, the role of miR-21-5p in the healing ...
    • Sorsa, Timo; Mäntylä, Päivi; Tervahartiala, Taina; Pussinen, Pirkko J.; Gamonal Aravena, Jorge Antonio; Hernández Ríos, Emma (John Wiley & Sons A/S, 2011-09)
    • Hernández Ríos, Emma; Martínez, Benjamín; Tejerina, José María; Valenzuela, María Antonieta; Gamonal Aravena, Jorge Antonio (2007)
      Matrix metalloproteinase (MMP)-13 is a collagenase involved in extracellular matrix degradation either by its direct degradative effects or by processing bioactive substrates. The aim of this study was to determine the ...
    • Hernández, Marcela; Baeza Paredes, Mauricio; Contreras Balbontín, Johanna; Sorsa, Timo; Tervahartiala, Taina; Valdés Salgado, Macarena; Chaparro, Alejandra; Hernández Ríos, Patricia (MDPI, 2020)
      Biomarkers represent promising aids in periodontitis, host-mediate diseases of the tooth-supporting tissues. We assessed the diagnostic potential of matrix metalloproteinase-8 (MMP-8), tartrate-resistant acid phosphatase-5 ...
    • Fernández, Javier; Jiménez, Constanza; Benadof, Dafna; Morales, Paulina; Astorga, Jéssica; Cáceres, Felipe; Hernández Ríos, Emma Marcela; Fernández, Alejandra; Valenzuela, Fernando (MDPI, 2022)
      Rosacea is a chronic inflammatory skin disease whose prevalence rates remain unknown in Chile. Laboratory benchmark testing for this disease is not useful, therefore, we aimed to evaluate the gingival crevicular fluid (GCF) ...