Now showing items 412-431 of 921

    • Busch, Alexander S.; Hagen, Casper P.; Main, Katharina M.; Pereira Scalabrino, Ana; Corvalán Aguilar, Camila; Almstrup, Kristian; Mericq, Verónica; Juul, Anders (Oxford Academic, 2017)
      Context: Although genetic factors play a pivotal role in male pubertal timing, genome-wide association studies have identified only a few loci. Genetic variation of follicle-stimulating hormone (FSH) action affects adult ...
    • Argüello, Graciela; Balboa, Elisa; Tapia, Pablo J.; Castro, Juan; Yáñez, María José; Mattar, Pamela; Pulgar Tejo, Rodrigo Enrique; Zanlungo, Silvana (MDPI, 2021)
      Niemann-Pick type C disease (NPCD) is a lysosomal storage disease (LSD) characterized by abnormal cholesterol accumulation in lysosomes, impaired autophagy flux, and lysosomal dysfunction. The activation of transcription ...
    • Loyola, David E.; Navarro, Cristell; Uribe, Paulina; García, Katherine; Mella, Claudia; Díaz, Diego; Valdes, Natalia; Martínez Urtaza, Jaime; Espejo Torres, Romilio (BioMed Central, 2015)
      Background: New strains of Vibrio parahaemolyticus that cause diarrhea in humans by seafood ingestion periodically emerge through continuous evolution in the ocean. Influx and expansion in the Southern Chilean ocean of ...
    • Hödar Quiroga, Christian; Moreno, Pablo; Genova, Alex di; Latorre, Mauricio; Reyes Jara, Angélica; Maass Sepúlveda, Alejandro; González Canales, Mauricio; Cambiazo Ayala, Liliana (Springer, 2012)
      Acidithiobacillus ferrooxidans is a chemolithoautotrophic acidophilic bacterium that obtains its energy from the oxidation of ferrous iron, elemental sulfur, or reduced sulfur minerals. This capability makes it of great ...
    • Mandakovic, Dinka; Cintolesi, Ángela; Maldonado, Jonathan; Mendoza, Sebastián; Aite, Meziane; Gaete, Alexis; Saitua, Francisco; Allende, Miguel; Cambiazo Ayala, Liliana; Siegel, Anne; Maass Sepúlveda, Alejandro; González Canales, Mauricio; Latorre Mora, Mauricio (Nature, 2020)
      The Atacama Desert is the most arid desert on Earth, focus of important research activities related to microbial biodiversity studies. In this context, metabolic characterization of arid soil bacteria is crucial to understand ...
    • Buchanan, Victoria L.; Wang, Yujie; Blanco, Estela; Graff, Mariaelisa; Albala Brevis, Cecilia; Burrows Argote, Raquel; Santos, José L.; Ángel, Barbara; Lozoff, Betsy; Voruganti, Venkata Saroja; Guo, Xiuqing; Taylor, Kent D.; Chen, Yii-Der Ida; Yao, Jie; Tan, Jingyi; Downie, Carolina; Highland, Heather M.; Justice, Anne E.; Gahagan, Sheila; North, Kari E. (Wiley, 2020)
      Background The genetic underpinnings of glycemic traits have been understudied in adolescent and Hispanic/Latino (H/L) populations in comparison to adults and populations of European ancestry. Objective To identify genetic ...
    • Galloway Peña, Jessica; Roh, Jung Hyeob; Latorre, Mauricio; Qin, Xiang; Murray, Barbara E. (PUBLIC LIBRARY SCIENCE, 2012-01-26)
      Recent studies have pointed to the existence of two subpopulations of Enterococcus faecium, one containing primarily commensal/community-associated (CA) strains and one that contains most clinical or hospital-associated ...
    • Castillo, Daniel; Espejo Torres, Romilio; Middelboe, Mathias (John Wiley & Sons, 2014)
      Flavobacterium psychrophilum is currently one of the most devastating fish pathogens worldwide causing considerable economic losses in salmonid aquaculture. Recently, attention has been drawn to the use of phages for ...
    • Mandakovic, Dinka; Glasner, Benjamín; Maldonado, Jonathan; Aravena, Pamela; González, Mauricio; Cambiazo Ayala, Verónica; Pulgar Tejo, Rodrigo (Frontiers Media, 2016)
      The gram negative facultative bacterium P. salmonis is the etiological agent of Salmonid Rickettsial Septicaemia (SRS), a severe disease that causes important economic losses in the global salmon farmer industry. Despite ...
    • Garmendia Miguel, María Luisa; Matus, O.; Mondschein, S.; Kusanovic, J. P. (Elsevier, 2018)
      Objectives: We examined if the guidelines for gestational weight gain (GWG) proposed by the Institute of Medicine (IOM) are the most suitable for Chilean women. Study design: Secondary analysis of records of single ...
    • Kuhn, Nathalie; Ponce, Claudio; Arellano, Macarena; Time, Alson; Sagredo, Boris; Donoso, José Manuel; Meisel, Lee A. (MDPI, 2020)
      Several phytohormones modulate ripening in non-climacteric fruits, which is triggered by abscisic acid (ABA). Gibberellins (GAs) are present during the onset of ripening in sweet cherry fruits, and exogenous gibberellic ...
    • Mora, Rodrigo; Weisstaub Nuta, Sergio (Soc. Medica de Santiago, 2016)
    • Sparling, Thalia M.; Cheng, Bryan; Deeney, Megan; Santoso, Marianne V.; Pfeiffer, Erin; Emerson, Jillian A.; Amadi, Florence Mariamu; Mitu, Khadija; Corvalán Aguilar, Camila; Verdeli, Helen; Araya, Ricardo; Kadiyala, Suneetha (Frontiers Media, 2021)
      Both malnutrition and poor mental health are leading sources of global mortality, disease, and disability. The fields of global food security and nutrition (FSN) and mental health have historically been seen as separate ...
    • Sepúlveda Quiñenao, Claudia Patricia; Rodríguez Silva, José Manuel; Díaz Castro, Francisco; Campo, Andrea del; Bravo Sagua, Roberto Francisco; Troncoso Cotal, Rodrigo Hernán (MDPI, 2022)
      Glucocorticoids (GC) are steroids hormones that drive circulating glucose availability through gluconeogenesis in the liver. However, alternative splicing of the GR mRNA produces two isoforms, termed GR alpha and GR beta. ...
    • Rodriguez, Juan; Monsalves Álvarez, Matías; Henriquez, Sandra; Llanos Silva, Miguel; Troncoso Cotal, Rodrigo (Elsevier Science, 2016-11)
      Glucocorticoids are involved in several responses triggered by a variety of environmental and physiological stimuli. These hormones have a wide-range of regulatory effects in organisms. Synthetic glucocorticoids are ...
    • Kallens, Violeta; Tobar Bachler, Nicolás; Molina, Jessica; Bidegain, Arantzazú; Smith, Patricio C.; Porras Espinoza, Omar; Martínez, Jorge (Wiley, 2017)
      Chronic inflammation and metabolic reprogramming have been proposed as hallmarks of cancer development. Currently, many of the functional clues between these two phenomena are studied under the integrative view of functional ...
    • Cornejo Espinoza, Verónica; Cabello, Juan Francisco; Colombo, Marta; Raimann Ballas, Erna (2007)
      The glucose transporter type 1 deficiency syndrome (GLUT-1 SD) (OMIM 606777) is an. inborn error of metabolism of brain. glucose transport. The characteristic clinical manifestations are seizures, hypotonia, developmental ...
    • Parada, Alejandra; Araya, Magdalena (SOC MEDICA SANTIAGO, 2010-10)
      The global prevalence of celiac disease is of one person per 250 inhabitants. The disease is induced by gluten, a peptide contained in wheat, rye and barley that during small intestinal digestion generates smaller peptides. ...
    • Díaz, E. O.; Galgani Fuentes, José; Aguirre, Carolina A. (BLACKWELL PUBLISHING, 2006-05)
      The purpose of this review was to examine the role of glycaemic index in fuel partitioning and body composition with emphasis on fat oxidation/storage in humans. This relationship is based on the hypothesis postulating ...
    • Retamal, Ignacio N.; Hernández, Romina; Melo, Francisco; Zapata, Paulina; Martínez Winkler, Jorge; Martínez, Constanza; Smith, Patricio C. (American Academy of Periodontology, 2017)
      Background: Glucose-derived metabolites may alter the structure and biologic properties of important proteins in periodontium, such as collagens. As a consequence, it is possible that collagen-binding cells may change their ...