Now showing items 424-443 of 921

    • Sparling, Thalia M.; Cheng, Bryan; Deeney, Megan; Santoso, Marianne V.; Pfeiffer, Erin; Emerson, Jillian A.; Amadi, Florence Mariamu; Mitu, Khadija; Corvalán Aguilar, Camila; Verdeli, Helen; Araya, Ricardo; Kadiyala, Suneetha (Frontiers Media, 2021)
      Both malnutrition and poor mental health are leading sources of global mortality, disease, and disability. The fields of global food security and nutrition (FSN) and mental health have historically been seen as separate ...
    • Sepúlveda Quiñenao, Claudia Patricia; Rodríguez Silva, José Manuel; Díaz Castro, Francisco; Campo, Andrea del; Bravo Sagua, Roberto Francisco; Troncoso Cotal, Rodrigo Hernán (MDPI, 2022)
      Glucocorticoids (GC) are steroids hormones that drive circulating glucose availability through gluconeogenesis in the liver. However, alternative splicing of the GR mRNA produces two isoforms, termed GR alpha and GR beta. ...
    • Rodriguez, Juan; Monsalves Álvarez, Matías; Henriquez, Sandra; Llanos Silva, Miguel; Troncoso Cotal, Rodrigo (Elsevier Science, 2016-11)
      Glucocorticoids are involved in several responses triggered by a variety of environmental and physiological stimuli. These hormones have a wide-range of regulatory effects in organisms. Synthetic glucocorticoids are ...
    • Kallens, Violeta; Tobar Bachler, Nicolás; Molina, Jessica; Bidegain, Arantzazú; Smith, Patricio C.; Porras Espinoza, Omar; Martínez, Jorge (Wiley, 2017)
      Chronic inflammation and metabolic reprogramming have been proposed as hallmarks of cancer development. Currently, many of the functional clues between these two phenomena are studied under the integrative view of functional ...
    • Cornejo Espinoza, Verónica; Cabello, Juan Francisco; Colombo, Marta; Raimann Ballas, Erna (2007)
      The glucose transporter type 1 deficiency syndrome (GLUT-1 SD) (OMIM 606777) is an. inborn error of metabolism of brain. glucose transport. The characteristic clinical manifestations are seizures, hypotonia, developmental ...
    • Parada, Alejandra; Araya, Magdalena (SOC MEDICA SANTIAGO, 2010-10)
      The global prevalence of celiac disease is of one person per 250 inhabitants. The disease is induced by gluten, a peptide contained in wheat, rye and barley that during small intestinal digestion generates smaller peptides. ...
    • Díaz, E. O.; Galgani Fuentes, José; Aguirre, Carolina A. (BLACKWELL PUBLISHING, 2006-05)
      The purpose of this review was to examine the role of glycaemic index in fuel partitioning and body composition with emphasis on fat oxidation/storage in humans. This relationship is based on the hypothesis postulating ...
    • Retamal, Ignacio N.; Hernández, Romina; Melo, Francisco; Zapata, Paulina; Martínez Winkler, Jorge; Martínez, Constanza; Smith, Patricio C. (American Academy of Periodontology, 2017)
      Background: Glucose-derived metabolites may alter the structure and biologic properties of important proteins in periodontium, such as collagens. As a consequence, it is possible that collagen-binding cells may change their ...
    • Andrews Guzmán, Mónica; Arredondo Olguín, Miguel Armando; Olivares Gronhert, Manuel (Aula Médica Ediciones, 2015)
      Objective: To investigate the relationship between oxidative stress and biochemical parameters and the expression of TXNIP, IL-6, IL-1 beta and TNF-alpha in peripheral mononuclear cells (PMCs) from type-2 diabetic patients. ...
    • Angel Badillo, Bárbara Karen; Ajnakina, Olesya; Albala Brevis, Cecilia Hortensia; Lera Marques, Lydia; Márquez Jara, Carlos Diego; Leipold, Leona; Bilovich, Avri; Dobson, Richard; Bendayan, Rebecca (MDPI, 2022)
      Growing evidence about the link between cognitive and physical decline suggests the early changes in physical functioning as a potential biomarker for cognitive impairment. Thus, we compared grip-strength trajectories ...
    • Giugliani, Roberto; Solano Villarreal, Martha Luz; Arellano Valdez, C. Araceli; Mahfoud Hawilou, Antonieta; Guelbert, Norberto; Correa Garzón, Luz Norela; Martins, Ana María; Acosta, Angelina; Cabello, Juan Francisco; Lemes, Aída; Schmitz Ferreira Santos, Mara Lucía; Amartino, Hernán (Sociedade Brasileira de Genética, 2014)
      This review aims to provide clinicians in Latin America with the most current information on the clinical aspects, diagnosis, and management of Hunter syndrome, a serious and progressive disease for which specific treatment ...
    • Klionsky, Daniel J.; Troncoso Cotal, Rodrigo; Chiong Lay, Mario; Díaz Araya, Guillermo; Glavic Maurer, Álvaro; Corbalán, Ramón; Matus, Soledad; Segura Aguilar, Juan; Hetz Flores, Claudio (Taylor & Francis inc., 2016)
    • Santibáñez, Juan Francisco; Hurtado, Claudia (ELSEVIER SCIENCE BV, 2005-11-21)
      Efforts have been made to develop a chemoprevention that selectively triggers apoptosis in malignant cancer cells. Here, we demonstrated that a mutated Ha-Ras activity is required in Anisomycin-induced apoptosis in transformed ...
    • Hödar Quiroga, Christian (Universidad de Chile, INTA, 2015)
    • Burrows, Raquel; Díaz Bustos, Erik; Sciaraffia Merino, Vito Gastón; Gattas, Vivien; Montoya C., Ana; Lera Marques, Lydia (SOC MEDICA SANTIAGO, 2008-01)
      Background: The increased. infantile obesity rates are related to faulty diery intake (DI) and physical activity (PA) habits, that are probably related to a prolonged stay at school during the day. Aim: To investigate DI ...
    • Ivanovic Marincovich, Daniza; Leiva, Boris P.; Pérez Muñoz, Hernán; Olivares Grohnert, Manuel; Díaz, Nora S.; Urrutia, María Soledad; Almagiá, Atilio F.; Toro, Triana D.; Miller, Patricio T.; Bosch, Enrique O.; Larraín, Cristián G. (Elsevier, 2004)
      This multifactorial study investigates the interrelationships between head circumference (HC) and intellectual quotient (IQ), learning, nutritional status and brain development in Chilean school-age children graduating ...
    • Lenoir Wijnkoop, Irene; Van der Beek, Eline M.; Garssen, Johan; Nuijten, Mark J. C.; Uauy Dagach-Imbarack, Ricardo (Frontiers Media, 2015)
      Background: Despite the interest in the impact of overweight and obesity on public health, little is known about the social and economic impact of being born large for gestational age or macrosomic. Both conditions are ...
    • Carreño, J.; Vyhmeister, G.; Grau, L.; Ivanovic Marincovich, Daniza (W B SAUNDERS CO LTD, 2006-04)
      Objective: In the last decades, the epidemiological and demographic transition in Chile has resulted in a considerable increase in diet-related noncommunicable chronic diseases. The aim of this study was to determine the ...
    • Burrows, Raquel; Correa Burrows, Paulina; Reyes Jedlicki, Marcela; Blanco, Estela; Albala Brevis, Cecilia; Gahagan, Sheila (Hindawi Publishing, 2015)
      Objective. To determine the optimal cutoff of the homeostasis model assessment-insulin resistance (HOMA-IR) for diagnosis of the metabolic syndrome (MetS) in adolescents and examine whether insulin resistance (IR), determined ...
    • Arredondo Olguín, Miguel; Mariotti, M.; Castillo, O.; Pérez Bravo, Francisco (Karger, 2020)