Two new antiinflammatory elemanolides from Centaurea chilensis
Negrete_Rosa_E.pdf (302.5Kb)Abstract
Two previously undescribed elemanolide esters, the 2-methylpropanoate and 2-methyl-2-propenoate of 11,13dehydromelitensin,
were iso1ated in the course of a bioassay-guided fractionation from the aeria1 parts of Centaurea
chilensis Hook, et Am" used traditionally to treat 'gout and rheumatism', The mixture ofboth substances exhibits antiinflammatory
activity in the carrageenan-induced paw edema assay.
Patrocinador
This work was possible because of financial
assistance from the University of Chile (DTI Q
2945 8923), International Foundation for Science
(F/1494-1) and Deutsche Forschungsgemeinschaft
(Germany).
Quote Item
Journal of Ethnopharmacology, Vol. 40, p. 149-153, 1993.
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