Peptides and metallic nanoparticles for biomedical applications
MetadataShow full item record
In this review, we describe the contribution of peptides to the biomedical applications of metallic nanoparticles. We also discuss strategies for the preparation of peptide-nanoparticle conjugates and the synthesis of the peptides and metallic nanoparticles. An overview of the techniques used for the characterization of the conjugates is also provided. Mainly for biomedical purposes, metallic nanoparticles conjugated to peptides have been prepared from Au and iron oxide (magnetic nanoparticles). Peptides with the capacity to penetrate the plasma membrane are used to deliver nanoparticles to the cell. In addition, peptides that recognize specific cell receptors are used for targeting nanoparticles. The potential application of peptide-nanoparticle conjugates in cancer and Alzheimer's disease therapy is discussed. Several peptide-nanoparticle conjugates show biocompatibility and present a low degree of cytotoxicity. Furthermore, several peptide-metallic nanoparticle conjugates are used f
Artículo de publicación SCOPUS
Quote ItemNanomedicine, Volumen 2, Issue 3, 2018, Pages 287-306
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile
Showing items related by title, author, creator and subject.
Block copolymers in the synthesis of gold nanoparticles. Two new approaches: Copolymer aggregates as reductants and stabilizers and simultaneous formation of copolymer aggregates and gold nanoparticles Leiva, Angel; Fuentes, Irma; Bossel, Esteban; Urzúa, Marcela; Méndez, Maximiliano; Pino, Maximiliano; Radïc, Deodato; Márquez, Valeria; González-Nilo, Fernando D. (John Wiley and Sons Inc., 2014)© 2014 Wiley Periodicals, Inc.In this article, innovative applications of amphiphilic triblock and pentablock copolymers in the synthesis of gold nanoparticles are reported. The synthesis of gold nanoparticles is performed ...
Formation of Copper Nanoparticles Supported onto Inclusion Compounds of alpha-cyclodextrin: A New Route to Obtain Copper Nanoparticles Silva, Nataly; Moris, Silvana; Herrera, Bárbara; Castro Díaz, Maximiliano; Kogan Bocian, Marcelo; Barrientos, Lorena; Yutronic Sáez, Nicolás; Jara Vergara, Paul (TAYLOR & FRANCIS LTD, 2010)This work presents the preparation of copper nanoparticles (CuNPs), using as support, inclusion compounds (ICs) formed by a-cyclodextrin (a-CD) with alkylamines as guests. These ICs provide a suitable environment to ...
The ultrasound-assisted synthesis of effective monodisperse nickel nanoparticles: magnetic characterization and its catalytic activity in CO2 methanation Vargas, E.; Romero Saez, M.; Denardin, J. C.; Gracia Caroca, Francisco Javier Esteban (2016)Homogeneous nickel nanoparticles were synthesized and supported over m-ZrO2 through a simple ultrasonic process. The microscopic and magnetic characterization of nanoparticles showed high quality and effective monodisperse ...