Now showing items 1-20 of 4333

    • Santulli, Gaetano; Monaco, Giovanni; Parra Ortiz, Valentina Maria; Morciano, Giampaolo (Frontiers Media, 2021)
    • Isla, Adolfo; Martínez Hernández, Jesús Eduardo; Levipan, Héctor A.; Haussmann, Denise; Figueroa, Jaime; Rauch, María Cecilia; Maracaja Coutinho, Vinicius; Yáñez, Alejandro (Frontiers Media SA, 2021)
      Piscirickettsia salmonis is a bacterial pathogen that severely impact the aquaculture in several countries as Canada, Scotland, Ireland, Norway, and Chile. It provokes Piscirickettsiosis outbreaks in the marine phase of ...
    • Córdova Delgado, Miguel Angel; Bravo, María Loreto; Cumsille, Elisa; Hill, Charlotte N.; Muñoz Medel, Matías; Pinto, Mauricio P.; Retamal, Ignacio N.; Lavanderos, María; Miquel, Juan Francisco; Rodríguez Fernández, María (BMC, 2021)
      Background: Fluoropyrimidine plus platinum chemotherapy remains the standard first line treatment for gastric cancer (GC). Guidelines exist for the clinical interpretation of four DPYD genotypes related to severe ...
    • Flores, Marcos; Avendaño, Victoria; Bravo, Jessica; Valdés, Cristian; Forero Doria, Óscar; Quitral, Vilma; Vilcanqui, Yesica; Ortiz Viedma, Jaime Alejandro (Hindawi, 2021)
      With the continuous increase in research on lipids, technologies and the development of chemical-analytical methods associated with the characterization and monitoring of different processes that involve modifications in ...
    • Caipo Coral, Leeanny Johary; Sandoval Paredes, Ana Maria; Sepúlveda, Betsabet; Fuentes Pérez, Edwar; Valenzuela Baez, Rodrigo Wladimir; Metherel, Adam H.; Romero Palacios, Nalda Marcela (MDPI, 2021)
      Commercialization of extra virgin olive oil (EVOO) requires a best before date recommended at up to 24 months after bottling, stored under specific conditions. Thus, it is expected that the product retains its chemical ...
    • Sandoval Bórquez, Alejandra; Polakovicova, Iva; Carrasco Véliz, Nicolás; Lobos González, Lorena; Riquelme, Ismael; Carrasco Avino, Gonzalo; Bizama Soto, Carolina del Carmen; Norero, Enrique; Owen, Gareth I.; Roa Strauch, Juan Carlos; Corvalán, Alejandro H. (BMC, 2021)
    • Parra Soto, Solange Liliana; Cowley, Emma S.; Rezende, Leandro F. M.; Ferreccio Keadi, Catterina; Mathers, John C.; Pell, Jill P.; Ho, Frederick K.; Celis Morales, Carlos (BMC, 2021)
      Background: Adiposity is a strong risk factor for cancer incidence and mortality. However, most of the evidence available has focused on body mass index (BMI) as a marker of adiposity. There is limited evidence on ...
    • Campanini Salinas, Javier Andrés; Andrades Lagos, Juan Andrés; Hinojosa Torres, Nicolás Antonio; Moreno Ruz, Fabián Eduardo; Alarcón, Pedro; González Rocha, Gerardo; Burbulis, Ian E.; Vásquez Velásquez, David (MDPI, 2021)
      There is an urgent need for the development of new antibiotics. Here, we describe the inhibitory activity of new quinone compounds against methicillin-resistant Staphylococcus aureus (ATCC(R) 43300), methicillin-sensitive ...
    • Parra Flores, Pablo Ignacio; Espitia Corredor, Jenaro Antonio; Espinoza Pérez, Claudio Andrés; Queirolo, Cristian; Ayala, Pedro; Brüggendieck, Francisca; Salas Hernández, Aimee; Pardo Jiménez, Viviana Gladys; Díaz Araya, Guillermo Antonio (Frontiers Media, 2021)
      Death of cardiac fibroblasts (CFs) by ischemia/reperfusion (I/R) has major implications for cardiac wound healing. In in vivo models of myocardial infarction, toll-like receptor 4 (TLR4) activation has been reported as ...
    • Flores, Marcos; Reyes García, Luis; Ortiz Viedma, Jaime Alejandro; Romero Palacios, Nalda Marcela; Vilcanqui Chura, Yesica Luz; Rogel, Cristian; Echeverría, Javier; Forero Doria, Óscar (MDPI, 2021)
      Avocado oil is considered a highly prized food due to its nutritional contribution. On the other hand, Aristotelia chilensis (Molina) Stuntz (Elaeocarpaceae), common name “maqui”, is an endemic fruit in Chile, well known ...
    • López Salas, Lucía; Cea, Inés; Borrás Linares, Isabel; Emanuelli, Tatiana; Robert Canales, Paz Soledad; Segura Carretero, Antonio; Lozano Sánchez, Jesús (MDPI, 2021)
      Phenolic compounds present in extra virgin olive oil (EVOO) could be retained in its byproducts during processing. Among them, hydroxytyrosol and its derivatives deserve special attention due to their health benefits ...
    • Arias Carrasco, Raúl Rubén; Giddaluru, Jeevan; Cardozo, Lucas E.; Martins Moraes, Felipe; Maracaja Coutinho, Vinicius; Nakaya, Helder I. (Sociedad de Biología de Chile, 2021)
      The current COVID-19 pandemic has already claimed more than 3.7 million victims and it will cause more deaths in the coming months. Tools that track the number and locations of cases are critical for surveillance and help ...
    • López Crisosto, Camila Paz; Díaz Vegas, Alexis; Castro, Pablo F.; Rothermel, Beverly A.; Bravo Sagua, Roberto Francisco; Lavandero González, Sergio Alejandro (SpringerNature, 2021)
      Subcellular organelles communicate with each other to regulate function and coordinate responses to changing cellular conditions. The physical-functional coupling of the endoplasmic reticulum (ER) with mitochondria allows ...
    • Fernández, Carolina; Torrealba, Natalia; Altamirano, Francisco; Garrido Moreno, Valeria Soraya; Vásquez Trincado, César; Flores Vergara, Raúl Alejandro; López Crisosto, Camila; Ocaranza, María Paz; Chiong Lay, Mario Martin; Pedrozo Cibils, Zully Rocío Evangelina; Lavandero González, Sergio (Public Library Science, 2021)
      Cardiac hypertrophy is the result of responses to various physiological or pathological stimuli. Recently, we showed that polycystin-1 participates in cardiomyocyte hypertrophy elicited by pressure overload and mechanical ...
    • Bolaños, Karen; Sánchez Navarro, Macarena; Tapia Arellano, Andreas; Giralt, Ernest; Kogan, Marcelo Javier; Araya, Eyleen (MDPI, 2021)
      Gold nanoparticles (AuNPs) have been shown to be outstanding tools for drug delivery and biomedical applications, mainly owing to their colloidal stability, surface chemistry, and photothermal properties. The biocompatibility ...
    • Pilaquinga, Fernanda; Morey, Jeroni; Fernández, Lenys; Espinoza Montero, Patricio; Moncada Basualto, Mauricio Javier; Pozo Martínez, Josué Santiago; Olea Azar, Claudio Alberto; Bosch, Rafael; Meneses, Lorena; Debut, Alexis; Piña, María de las Nieves (Dove Medical, 2021)
      Purpose: The importance of studying polyphenolic compounds as natural antioxidants has encouraged the search for new methods of analysis that are quick and simple. The synthesis of silver nanoparticles (AgNPs) using plant ...
    • Pérez Arancibia, Rodrigo Nicolás; Ordóñez, José Luis; Rivas, Alexis; Pihán, Philippe; Sagredo, Alfredo; Ahumada, Ulises; Barriga, Andrés; Seguel, Ivette; Cárdenas, César; Vidal, René L.; Hetz Flores, Claudio Andres; Delporte Vergara, Carla Luz (Public Library Science, 2021)
      Accumulation of misfolded proteins in the brain is a common hallmark of most age-related neurodegenerative diseases. Previous studies from our group identified the presence of anti-inflammatory and antioxidant compounds ...
    • Fernández Galleguillos, Carlos; Quesada Romero, Luisa; Puerta, Adrián; Padrón, José M.; Souza, Ernane; Romero Parra, Javier Hernán; Simirgiotis, Mario J. (MDPI, 2021)
      Gaultheria pumila (Ericaceae) (known as Chaura or Mutilla) is a Chilean native small shrub that produces berry fruits consumed by local Mapuche people. In this study, the chemical fingerprinting and antioxidant, enzyme ...
    • Lizama, Catherine; Romero Parra, Javier Hernán; Andrade, Daniel; Riveros, Felipe; Bórquez, Jorge; Ahmed, Shakeel; Venegas Salas, Luis; Cabalín, Carolina; Simirgiotis, Mario J. (MDPI, 2021)
      Haloarchaea are extreme halophilic microorganisms belonging to the domain Archaea, phylum Euryarchaeota, and are producers of interesting antioxidant carotenoid compounds. In this study, four new strains of Haloarcula sp., ...
    • Sánchez, Sofía V.; Navarro Martínez, Nicolás Matías; Catalán Figueroa, Johanna; Morales Montecinos, Javier Octavio (Frontiers Media, 2021)
      Urinary tract infection (UTI) is one of the most common reasons for antibiotic treatment. Nevertheless, uropathogens are steadily becoming resistant to currently available therapies. In this context, nanotechnology emerges ...