Now showing items 4101-4120 of 4968

    • Gómez Jeria, Juan; Soto Morales, Francisco; Larenas Gutiérrez, Gipsy (University of Tehran, 2003-09-06)
      We present here the results of a formal structure-property relationship study carried out for 1 CB - and 2 CB -mediated inhibition of adenylyl cyclase (ADC) by a group of classical cannabinoid derivatives. The wave ...
    • Gómez Jeria, Juan; Morales, Raúl; Reyes, Luis M. (The American Astronomical Society, 1985-08-08)
      Calculations at the HFj4-31G level were performed for the C2S2 molecule. The ground state is predicted to be 3Lg - and is of di radical nature. The lowest lying ionic and excited states were also analyzed. We conclude that ...
    • Gómez Jeria, Juan; Parra Mouchet, Julia; Morales Lagos, D. (John Wiley & Sons, lnc., 1990-01-30)
      A model for catecholamine storage in vesicles is analyzed within the ,CRI CNDO/2 approach inc1uding conlinuum solvenl crfcels. The model considers lhe approach of calionic norepinephrine (NE) 10 a positively charged ...
    • Gómez Jeria, Juan (American Pharmaceutical Association, 1982-08-04)
    • Gómez Jeria, Juan (Elsevier, 1984-06-28)
      The use in QSAR studies of parameters measuring the ability of an unlabeled rnolecule to compete for the binding site with a . radioligand is examined. 1t is shown that in order to employ them within a recently ...
    • Contreras Vallejos, Erick; Utreras Puratich, Elías; González Billault, Christian (Elsevier, 2012)
      Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase that is mostly active in the nervous system, where it regulates several processes such as neuronal migration, actin and microtubule dynamics, axonal ...
    • Catalán, Tamara P.; Wozniak, Aniela; Niemeyer Marich, August; Kalergis, Alexis M.; Bozinovic, Francisco (Elsevier, 2012)
      Although the study of thermoregulation in insects has shown that infected animals tend to prefer higher temperatures than healthy individuals, the immune response and energetic consequences of this preference remain ...
    • Cárcamo, José J.; Aliaga, Alvaro E.; Clavijo Campos, Ernesto; Brañes, Manuel R.; Campos Vallette, Marcelo (Elsevier, 2012)
      The Raman spectra (1800–200 cm−1) of isolated dried collagen types I and III were recorded at different times after shockwave (SW) application in aqueous media. SWs were applied in a single session. One week after the ...
    • Cárcamo, José J.; Aliaga, Aalvaro E.; Clavijo Campos, Ernesto; Brañes, M.; Campos Vallette, Marcelo (Johm Wiley, 2012)
      Important improvements of diseases of the rotator cuff supraspinatus tendons are seen after shock wave (SW) treatment. Neo-angiogenesis stimulation and hypercellularization result from short periods of treatment. The present ...
    • Gómez Jeria, Juan; Cassels Niven, Bruce; Saavedra Aguilar, Juan Carlos (Elsevier Science, 1987-06-05)
      The electronic structure of 1-(2,5-dimethoxy-4-nitrophenyl)-2-aminopropane (DON) was calculated at the CND0/2 level, and the racemic compound was synthesized and found to be hallucinogenic at doses of 4 mg. DON differs ...
    • Gómez Jeria, Juan; Lagos Arancibia, Luis; Sobarzo Sánchez, Eduardo (Sociedad Chilena de Química, 2002-12-02)
      A ZINDO/1 quantum-chemical structure-affinity relationship study is presented for the interaction of a group of 7-arylidenenaltrexones with m , k and d opioid receptors. From this work it is concluded that: 1. The ...
    • Dajas-Bailador, Federico A.; Asencio, Marcelo; Bonilla, Carolina; Scorza, Ma. Cecilia; Echeverry, Carolina; Reyes Parada, Miguel; Silveira, Rodolfo; Protais, Philippe; Russell, Graeme; Cassels Niven, Bruce; Dajas, Federico (Elsevier Science Inc., 1998-07-07)
      The dopaminergic and antioxidant properties of pukateine [(R)-11-hydroxy-1,2-methylenedioxyaporphine, PUK], a natural aporphine derivative, were analyzed in the rat central nervous system. At dopamine (DA) D1 ([3H]-SCH ...
    • Contreras Ramos, Renato; Gómez Jeria, Juan (American Chemical Society, 1983-07-19)
      SCF-CNDO/2 calculations, including the continuum solvent effects via an extended version of the generalized Born formula, have been performed for H30+··.(H20) •.•. OH- and (H20) •... Hp+ ... OH- species (n = 0,1,2). The ...
    • Cavé, André; Ocquemiller, Reynaldh; Cassels Niven, Bruce; Leboeuf, Michel; Rasamizafy, Sabino; Roblot, François; Davoust, Daniel; Deverre, J. R.; Khan, K. C.; Hadi, A. H. A. (American Chemical Society, 1985-11-25)
      The stem bark of Artabottys venustus yielded 0.34% of crude bases, mostly known aporphinoids and berbinoids. One of the minor constituents, (-)-artavenustine (12), is a new member of the rare class of catecholic isoquinoline ...
    • Castro Castillo, Vicente; Rebolledo-Fuentes, Marco; Cassels Niven, Bruce (SOC CHILENA QUIMICA, 2009-07-20)
      The synthesis of 4,5,8,12b-tetrahydroisoindolo[1,2-a]isoquinolin-8-ones is reviewed The unsubstituted parent compound, a series of fourteen A-ring-substituted derivatives, most of them new, and some of their doubly benzylic, ...
    • Cassels Niven, Bruce; Asencio, Marcelo; Conget, Paulette; Speisky Cosoy, Hernán; Videla Cabrera, Luis; Lissi Gervaso, Eduardo A. (The Italian Pharmacological Society, 1994-07-18)
      The antioxidative properties of the aporphines boldine, glaucine and apomorphine, and of the benzyltetrahydroisoquinolines (f)-coclaurine and (f)-norarmepavine were compared in the brain homogenate autoxidation model. ...
    • Tadic, Dragana; Cassels Niven, Bruce; Laprévote, Olivier; Cavé, André (American Chemical Society, 1988-09-22)
      The 13C-nmr chemical shifts of onychine (l-methyl4-aza8uoren-9-one) [l] were assigned with the aid ofheternnuclear 2D-nmr spectraand these results were used to interpret the 13C nmr spectra of several other synthetic duorenones.
    • Iturriaga-Vásquez, Patricio; Cassels Niven, Bruce; Ivorra, M. Dolores; D’Ocon, M. Pilar (Sociedad Chilena de Química, 2006-09)
      Benzyltetrahydroisoquinoline (BTHIQ) molecules are able to adopt widely differing conformations that depend on the presence or absence of N-substituents. To assess the possible role of BTHIQ conformation on the affinity ...
    • Villablanca, Eduardo J.; Renucci, Armand; Sapède, Dora; Lec, Valérie; Soubiran, Fabien; Sandoval, Pablo C.; Dambly-Chaudiere, Christine; Ghysen, Alain; Allende Connelly, Miguel (WILEY-LISS, 2006-03-21)
      The sensory organs of the zebrafish lateral-line system (neuromasts) originate from migrating primordia that move along precise pathways. The posterior primordium, which deposits the neuromasts on the body and tail of ...
    • Benson, Micah J.; Pino-Lagos, Karina; Rosemblatt Silber, Mario César; Noelle, Randolph J. (ROCKEFELLER UNIV PRESS, 2007-06-25)
      We demonstrate that all-trans retinoic acid (RA) induces FoxP3 adaptive T regulatory cells (A-Tregs) to acquire a gut-homing phenotype ( 4 7 CC chemokine receptor 9 ) and the capacity to home to the lamina ...