Now showing items 4121-4140 of 4968

    • Cassels Niven, Bruce; Cavé, André; Boeuf, Michelle (American Chemical Society, 1986-07-29)
    • Cassels Niven, Bruce; Urzúa, Alejandro (American Chemical Society, 1985-01-21)
      The stem bark of Laurelia sempervirens R. et P. (Monimiaceae, subfamily Atherospermoideae) is a rich source of aporphinoids and has also been shown to contain a complex mixture of unidentified bisbenzylisoquinolines (1). ...
    • Urzúa, Alejandro; Comin, J.; Cassels Niven, Bruce; Sánchez, E. (Universidad Técnica del Estado (Chile). Dirección de Investigaciones Científicas y Tecnológicas, 1978-01)
      De las cortezas de tronco de Laurelia sempervirens (R. et Pav.) TUL y de Laurelia philippiana. Looser fueron aislados e identificados los siguientes alcaloides: liriodenina (I),oxorantenina ( II ), ...
    • Barrientos, L.; Allende, P.; Orellana, C.; Jara Vergara, Paul (Elsevier, 2012)
      An ordered self-assembly of copper, silver and gold nanoparticles onto crystal faces of a-cyclodextrin/1- octanethiol and 2a-cyclodextrin/1-octylamine inclusion complexes by means of physical vapor deposition (magnetron ...
    • Urzúa, A.; Cassels Niven, Bruce; Comin, J.; Sánchez, E. (Universidad de Santiago de Chile, 1978-01)
      De las cortezas de tronco de Laurelia sempervirens (R. et Pav.)Tul y de Laurelia philippiana Looser fueron aislados e identificados los siguientes alcaloide: liriodenina (I), oxonantenina (II),nornantenina (III), aterolina ...
    • Araya Maturana, Ramiro; Delgado Castro, Tomás; Gárate, Mario; Ferreira Parker, Jorge; Pavani, Mario; Pessoa Mahana, Hernán; Cassels Niven, Bruce (Elsevier Science Ltd., 2002-01-29)
      Abstract—A set of structurally related compounds incorporating a carbonyl group in the ortho position withregard to a phenol function were tested against the TA3 mouse carcinoma cell line and its multidrug-resistant variant ...
    • Araya Maturana, Ramiro; Cardona, Wilson; Cassels Niven, Bruce; Delgado Castro, Tomás; Ferrada Parker, Jorge; Miranda, Dante; Pavani, Mario; Pessoa Mahana, Hernán; Soto Delgado, Jorge; Weiss López, Boris (Elsevier Ltd., 2006-02-28)
      Abstract—A series of tricyclic hydroquinones, incorporating a carbonyl group in the ortho position relative to the phenol function, were tested as inhibitors of oxygen uptake against the TA3 mouse carcinoma cell line and ...
    • Cassels Niven, Bruce; Asencio, Marcelo (EDITORIAL BOARD, 2007-12-01)
      The aporphine alkaloids constitute the second-largest group of isoquinoline alkaloids. Nevertheless, only a relatively small number of natural aporphines and their derivatives have been studied from a pharmacological ...
    • Cabedo, Nuria; Protais, Philippe; Cassels Niven, Bruce; Cortes, Diego (American Chemical Society and American Society of Pharmacognosy, 1998-01-15)
      (R)-(+)-nor-Roefractine (1) was synthesized by the Bischler-Napieralski route, using asymmetric reduction of the 1,2-didehydro precursor imine with sodium (S)-N-CBZ-prolinyloxyborohydride. Compound 1 was able to displace ...
    • Caroli Rezende, Marcos; Núñez, Christián; Sepúlveda Boza, Silvia; Cassels Niven, Bruce; Hurtado Guzmán, Claudio (Marcel Dekker, Inc., 2001-09-18)
      The preparation of the sulfoxides and the sulfones of two centrally active alkylthioamphetamine salts, ( )-1-(4-methylthiophenyl)- 2-aminopropane hydrochloride (2) (MTA HCl) and ( )-1-(2,5-dimethoxy-4-ethylthiophenyl ...
    • Carrasco, N.; Urzúa, A.; Cassels Niven, Bruce (American Chemical Society, 1973-07-23)
    • Andreu, Inmaculada; Cortes, Diego; Protais, Philippe; Cassels Niven, Bruce; Chagraoui, Abdeslam; Cabedo, Nuria (Elsevier Science Ltd., 1999-11-15)
      AbstractÐThe preparation of N-methyl-BTHIQ (4) from N-phenylethyl-phenacetamide (1) by cyclization, reduction and N-alkyl- ation in acid medium has been achieved in good yield in a `one-pot' procedure. Acylation of imine ...
    • Aguirre, María C.; Delporte Vergara, Carla; Backhouse Erazo, Nadine; Erazo, Silvia; Letelier Muñoz, María Eugenia; Cassels Niven, Bruce; Silva, Ximena; Alegría, Sergio; Negrete Córdova, Rosa (Elsevier Ltd., 2006-05-11)
      Abstract—Leaf extracts of Ugni molinae Turcz. are used in the Chilean cosmetic industry on the assumption that they have decongestant, regenerative, and anti-aging properties. A bioassay-guided fractionation of this plant ...
    • Acuña Castillo, Claudio; Scorza, Cecilia; Reyes Parada, Miguel; Cassels Niven, Bruce; Huidobro Toro, Juan Pablo (Elsevier Science Inc., 2000-06-06)
      To assess the pharmacodynamic profile of ALEPH-2, a phenylisopropylamine derivative with alleged anxiolytic and hallucinogenic properties, Xenopus laevis oocytes were microinjected with either of the rat cRNA for the ...
    • Acuña Castillo, Claudio; Villalobos, Claudio; Moya, Pablo R.; Sáez, Patricio; Cassels Niven, Bruce; Huidobro Toro, Juan Pablo (Nature Publishing Group, 2002-04-04)
      1 The pharmacological pro®le of a series of (+)-2,5-dimethoxy-4-(X)-phenylisopropylamines (X=I, Br, NO2, CH3, or H) and corresponding phenylethylamines, was determined in Xenopus laevis oocytes injected with cRNA coding ...
    • Sobarzo Sánchez, Eduardo; Cassels Niven, Bruce; Castedo, Luis (Georg Thieme, 2003-08-25)
      Several 2,3-dihydro-7H-dibenzo[de,h]quinolin-7-ones and 7H-dibenzo[de,h]quinolin-7-ones were catalytically hydro­genated over PtO2 in acetic acid to afford 7-hydroxyquinoline and quinolone derivatives with reduced benzene rings.
    • Rodríguez Díaz, Maité; Delporte Vergara, Carla; Cartagena, Carlos; Cassels Niven, Bruce; González, Patricia; Silva, Ximena; León, Fredy; Wessjohann, Ludger A. (Royal Pharmaceutical Society, 2011-01-18)
      Objectives Quillaic acid is the major aglycone of the widely studied saponins of the Chilean indigenous tree Quillaja saponaria Mol. The industrial availability of quillaja saponins and the extensive functionalisation ...
    • Liberto, Melina Di; Svetaz, Laura; Furlán, Ricardo L. E.; Zacchino, Susana; Delporte Vergara, Carla; Novoa, Marco A.; Asencio, Marcelo; Cassels Niven, Bruce (EDITORIAL BOARD, 2010-05-20)
      A saponin-rich extract of Phytolacca dioica L. berries, its acid hydrolysate, and its major aglycone, phytolaccagenin, were assayed for antifungal activity against ATCC standard cultures of Candida albicans and Cryptococcus ...
    • Ravanal, María Cristina; Espinosa, Yeison; Rosa, Lorena; Vaca Cerezo, Inmaculada; Polanco, Rubén; Eyzaguirre, Jaime; Levicán, Gloria; Chávez, Renato (Springer, 2012)
      The heterologous secretion of xylanase B from Penicillium purpurogenum using glucose as inducer was performed in Aspergillus nidulans. For this purpose, plasmid pEVXB, containing the xylanase B cDNA (including its own ...
    • Iturriaga-Vásquez, Patricio; Carbone, Annalisa; García Beltrán, Olimpo; Livingstone, Phil D.; Biggin, Philip C.; Cassels Niven, Bruce; Wonnacott, Susan; Zapata-Torres, Gerald; Bermúdez, Isabel (The American Society for Pharmacology and Experimental Therapeutics, 2010-06-14)
      The Erythrina alkaloids erysodine and dihydro- -erythroidine (DH E) are potent and selective competitive inhibitors of 4 2 nicotinic acetylcholine receptors (nAChRs), but little is known about the molecular determinants ...