Now showing items 4861-4880 of 4970

    • Soto, Marco A.; González, Carlos; Lissi Gervaso, Eduardo A.; Vergara Montecinos, Cecilia; Latorre, Ramón (AMER PHYSIOLOGICAL SOC, 2002-03)
      We studied the effect of H2O2 on the gating behavior of large-conductance Ca2+-sensitive voltage-dependent K+ (K-V,K-Ca) channels. We recorded potassium currents from single skeletal muscle channels incorporated into ...
    • Sorensen, J. B.; Cha, A.; Latorre, Ramón; Rosenman, Eduardo; Bezanilla, Francisco (ROCKEFELLER UNIV PRESS, 2000-02)
      When attached outside the voltage-sensing S4 segment of the Shaker potassium channel, the fluorescent probe tetramethylrhodamine (TMRM) undergoes voltage-dependent fluorescence changes (Delta F) due to differential interaction ...
    • Orio, Patricio; Torres, Yolima; Rojas, Patricio; Carvacho, Ingrid; García, María L.; Toro, Ligia; Valverde, Miguel A.; Latorre, Ramón (ROCKEFELLER UNIV PRESS, 2006-02)
      High conductance, calcium- and voltage-activated potassium (BK, MaxiK) channels are widely expressed in mammals. In some tissues, the biophysical properties of BK channels are highly affected by coexpression of regulatory ...
    • Orio, Patricio; Latorre, Ramón (ROCKEFELLER UNIV PRESS, 2005-04)
      High conductance, calcium- and voltage-activated potassium (BK) channels are widely expressed in mammals. In some tissues, the biophysical properties of BK channels are highly affected by coexpression of regulatory (beta) ...
    • Orellana, W.; Vásquez, Sergio O. (AMERICAN PHYSICAL SOC, 2006-09)
      The inclusion and encapsulation of terthiophene (T3) molecules inside zigzag single-walled carbon nanotubes (CNT's) is addressed by density functional calculations. We consider the T3 molecule inside six semiconducting ...
    • Orellana, W.; Gutiérrez, G.; Menéndez Proupin, Eduardo; Rogan Castillo, José; García, G.; Manoun, B.; Saxena, S. (PERGAMON-ELSEVIER SCIENCE LTD, 2006-09)
      Structural and electronic properties of Ti3Si0.5Ge0.5C2 under pressure up to 80 GPa are studied by means of first principles calculation based on density functional theory (DFT). The total energy, lattice parameters and ...
    • Olcese, Riccardo; Latorre, Ramón; Toro, Ligia; Bezanilla, Francisco; Stefani, Enrico (ROCKEFELLER UNIV PRESS, 1997-11)
      Prolonged depolarization induces a slow inactivation process in some Ki channels. We have studied ionic and gating currents during long depolarizations in the mutant Shaker H4-Delta(6-46) K+ channel and in the nonconducting ...
    • Olcese, Riccardo; Sigg, Daniel; Latorre, Ramón; Bezanilla, Francisco; Stefani, Enrico (ROCKEFELLER UNIV PRESS, 2001-02)
      In Shaker K+ channel, the amino terminus deletion Delta6-46 removes fast inactivation (N-type) unmasking a slow inactivation process. In Shaker Delta6-46 (Sh-IR) background, two additional mutations (T449V-I470C) remove ...
    • Leiva, Angel; Urzúa Acevedo, Marcela; Gargallo, Ligia; Radic, Deodato (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2006-07-01)
      A comparative study of spread and adsorbed monolayer of poly(ethylene oxide)s of different molecular weight hydrophobically modified with alkyl isocyanates of different length chain is reported. The modification of the ...
    • González, Carlos; Rosenman, Eduardo; Bezanilla, Francisco; Álvarez Araya, Osvaldo; Latorre, Ramón (NATL ACAD SCIENCES, 2001-08-14)
      Upon depolarization positive charges contained in the transmembrane segment S4 of voltage-dependent channels are displaced from the cytoplasmic to the external milieu, This charge movement leads to channel opening. In ...
    • Latorre, Ramón; Olcese, Riccardo; Basso, Claudia; González, Carlos; Muñoz, Fabián; Cosmelli, Diego; Álvarez Araya, Osvaldo (ROCKEFELLER UNIV PRESS, 2003-10)
      Animal and plant voltage-gated ion channels share a common architecture. They are made up of four subunits and the positive charges on helical S4 segments of the protein in animal K+ channels are the main voltage-sensing ...
    • Hebeisen, Simon; Heidtmann, Hannelore; Cosmelli, Diego; González, Carlos; Poser, Barbara; Latorre, Ramón; Álvarez Araya, Osvaldo; Fahlke, Christoph (BIOPHYSICAL SOCIETY, 2003-04)
      CIC-4 and CIC-5 are mammalian CIC isoforms with unique ion conduction and gating properties. Macroscopic current recordings in heterologous expression systems revealed very small currents at negative potentials, whereas a ...
    • Gruberg, Edward; Dudkin, Elizabeth; Wang, Yuan; Marín Game, Gonzalo; Salas, Carlos; Sentis, Elisa; Letelier Parga, Juan; Mpodozis Marín, Jorge; Malpeli, Joseph; Cui, He; Ma, Rui; Northmore, David; Udin, Susan (SOC NEUROSCIENCE, 2006-10-11)
    • González, Juan; Reyes, Francisca; Salas, Carlos; Santiago, Margarita; Codriansky, Yael; Colihueque, Nelson; Silva Ascencio, Herman (SOCIEDAD BIOLGIA CHILE, 2006)
      One of the fungal pathogens that causes more agriculture damage is Botrytis cinerea. Botrytis is a constant threat to crops because the fungus infects a wide range of host species. both native and cultivated. Furthermore, ...
    • Sarrazín, Andrés F.; Villablanca, Eduardo J.; Núñez, Viviana; Sandoval, Pablo; Ghysen, Alain; Allende Connelly, Miguel (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2006-07-15)
      The lateral line system comprises an array of mechanosensory organs, the neuromasts, distributed over the body surface. Each neuromast consists of a patch of mechanosensory hair cells surrounded by support cells. We show ...
    • Peña, Octavio; Moure, C.; Barahona Huenchumil, Patricia Mabel; Baibich, M.; Martínez, G. (ELSEVIER SCIENCE BV, 2006-10-01)
      Partial substitutions of Mn by a transition metal Me in the rare-earth manganites REMexMn1-xO3 results in the simultaneous presence of Mn3+ and Mn4+, triggering double exchange ferromagnetic mechanisms. The RE sublattice ...
    • González, Carlos; Rosenman, Eduardo; Bezanilla, Francisco; Álvarez Araya, Osvaldo; Latorre, Ramón (ROCKEFELLER UNIV PRESS, 2000-02)
      In Shaker K+ channels depolarization displaces outwardly the positively charged residues of the S4 segment. The amount of this displacement is unknown, but large movements of the S4 segment should be con strained by the ...
    • Ezquer, Fernando; Núñez González, Marco; Rojas, Alejandro; Asenjo de Leuze, Juan; Israel Jacard, Yedy (SOCIEDAD BIOLGIA CHILE, 2006)
      Levels of body iron should be tightly controlled to prevent the formation of oxygen radicals. lipoperoxidation. genotoxicity, and the production of cytotoxic cytokines, which result in damage to a number of organs. Enterocytes ...
    • Díaz Cuevas, Laín; Meera, Pratap; Amigo, Julio; Stefani, Enrico; Álvarez Araya, Osvaldo; Toro, Ligia; Latorre, Ramón (AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 1998-12-04)
      We investigated the role of individual charged residues of the S4 region of a MaxiK channel (hSlo) in channel gating, We measured macroscopic currents induced by wild type (WT) and point mutants of hSlo in inside-out ...
    • Chamorro, Eduardo; Santos, J. C.; Escobar, C. A.; Pérez López, Patricia (ELSEVIER, 2006-11-11)
      The philicity indices, omega(N), and omega(+)(S), characterize a charge transfer process occurring at constant spin number, and the spin polarization for a process at constant number of electrons, respectively. These ...