Browsing by Author "XX568981"

Now showing items 41-60 of 82

    • Gold nanoparticles stabilized with beta cyclodextrin -2 - amino -4 -(4-chlorophenyl) thiazole complex: a ... 
      Asela, I.; Noyong, M.; Simon, U.; Andrades Lagos, Juan Andrés; Campanini Salinas, J.; Vásquez Velásquez, David; Kogan Bocian, Marcelo; Yutronic Sáez, Nicolás; Sierpe, R. (Public Library Science, 2017)
      While 2-amino-4-(4-chlorophenyl)thiazole (AT) drug and thiazole derivatives have several biological applications, these compounds present some drawbacks, such as low aqueous solubility and instability. A new complex of ...
    • Growth Kinetics of Gold Nanorods Synthesized by a Seed-Mediated Method Under pH Acidic Conditions 
      Almada, M.; Ruiz, E. D.; Ibarra Hurtado, J.; Hassan, N.; Kogan Bocian, Marcelo; Cadena Nava, R. D.; Valdés, M. A.; Juarez, J. (Amer Scientific, 2016)
      A systematic study of the effect of ascorbic acid concentration on the growth kinetics of gold nanorods under pH acidic conditions was done. We employed the seed-mediated approach at pH 1.25 using different ascorbic acid/Au+3 ...
    • How Changes in the Sequence of the Peptide CLPFFD-NH2 Can Modify the Conjugation and Stability of Gold ... 
      Olmedo, Ivonne; Araya, Eyleen; Sanz, Fausto; Medina, Elias; Arbiol, Jordi; Toledo, Pedro; Álvarez Lueje, Alejandro; Giralt, Ernest; Kogan Bocian, Marcelo (American Chemical Society, 2008-05-30)
      In a previous work, we studied the interaction of -amyloid fibrils (A ) with gold nanoparticles (AuNP) conjugated with the peptide CLPFFD-NH2. Here, we studied the effect of changing the residue sequence of the ...
    • How changes in the sequence of the peptide CLPFFD-NH2 can modify the conjugation and stability of gold ... 
      Olmedo Alegría, Ivonne Odette; Araya, Eyleen; Sanz, F.; Medina Consuegra, Elías Daniel; Arbiol, Jordi; Toledo, P.; Álvarez Lueje, Alejandro; Giralt, Ernest; Kogan Bocian, Marcelo (AMER CHEMICAL SOC, 2008-06)
      In a previous work, we studied the interaction of P-amyloid fibrils (A beta) with gold nanoparticles (AuNP) conjugated with the peptide CLPFFD-NH2. Here, we studied the effect of changing the residue sequence of the peptide ...
    • Implementación de una técnica de extracción y purificación de restos de pólenes para su caracterización con ... 
      Acuña Prado, Marcela Carolina (Universidad de Chile, 2014)
      El polen es el elemento germinal masculino de las plantas con flores (Gimnospermas y Angiospermas). Se produce en grandes cantidades, posee un tamaño microscópico, es altamente resistente a la acción de agentes químicos, ...
    • Implicancias farmacéuticas de la conjugación de péptidos a nanopartículas de oro : efectos sobre la interacción ... 
      Guerrero Rivera, Simón Juan (Universidad de Chile, 2013)
      Al exponer diferentes Nanomateriales (NM) al plasma sanguíneo estos son reconocidos por biomoléculas, formándose una nano-bio interface denominada corona de proteínas (CP), en la que se observan interacciones dinámicas ...
    • Improving cell penetration of gold nanorods by using an amphipathic arginine rich peptide 
      Riveros Salvatierra, Ana; Eggeling, Cynthia; Riquelme Barrios, Sebastián; Adura, Carolina; López Iglesias, Carmen; Guzmán, Fanny; Araya Fuentes, Eyleen; Almada, Mario; Juárez, Josue; Valdez, Miguel A.; Fuentevilla Morgado, Ignacio; López, Olga; Kogan Bocian, Marcelo (Dove Medical Press, 2020)
      Introduction: Gold nanorods are highly reactive, have a large surface-to-volume ratio, and can be functionalized with biomolecules. Gold nanorods can absorb infrared electromagnetic radiation, which is subsequently dispersed ...
    • Improving gold nanorod delivery to the central nervous system by conjugation to the shuttle Angiopep-2 
      Velasco Aguirre, Carolina; Morales Zavala, Francisco; Salas Huenuleo, Edison; Gallardo Toledo, Eduardo; Andonie, Oscar; Muñoz, Luis; Rojas, Ximena; Acosta, Gerardo; Sánchez Navarro, Macarena; Giralt, Ernest; Araya, Eyleen; Albericio, Fernando; Kogan Bocian, Marcelo (Future Medicine, 2017)
      Aim: To improve the in vivo delivery of gold nanorods (GNRs) to the central nervous system of rats, these gold nanoparticles were conjugated to Angiopep-2, a shuttle peptide that can cross the blood-brain barrier. Materials ...
    • Improving the brain delivery of gold nanoparticles by conjugation with an amphipathic peptide 
      Guerrero, Simon; Araya, Eyleen; Fiedler Temer, Jenny; Arias, J.; Adura, Carolina; Albericio, Fernando; Giralt, Ernest; Arias, José; Fernández, María Soledad; Kogan Bocian, Marcelo (2010)
      Background & aims: Gold nanoparticles (GNPs) have promising applications for drug delivery as well as for the diagnosis and treatment of several pathologies, such as those related to the CNS. However, GNPs are retained in ...
    • Inhibition of HIV-2(ROD) replication in a lymphoblastoid cell line by the alpha 1-antitrypsin Portland ... 
      Bahbouhi, B.; Bendjennat, M.; Chiva, C.; Kogan Bocian, Marcelo; Albericio, F.; Giralt, Ernest; Seidah, N. G.; Bahraoui, E. (EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2001-11)
      We investigated the effects of alpha1-antitrypsine Portland variant (alpha1-PDX) and decanoylRVKRchloromethylketone (decRVKRcmk) on HIV-2(ROD) replication in the Jurkat lymphoblastoid cell line. To this end, cells were ...
    • Interface analysis of Ag/n-type Si contacts in n-type PERT solar cells. 
      Ferrada, Pablo; Rudolph, Dominik; Portillo, Carlos; Adrián, Adrián; Correa Puerta, Jonathan; Sierpe, Rodrigo; Campo, Valeria del; Flores, Marcos; Corrales, Tomás P.; Henriquez, Ricardo; Kogan Bocian, Marcelo; Lossen, Jan (Wiley, 2020)
      To increase efficiencies of bifacial solar cells, emitter, back surface field (BSF), and metal patterns must be optimized. We study the influence of paste volume, through multiple prints, of two silver pastes on the contact ...
    • Ion pair method to determine the CTAB content in gold nanorods samples 
      Adura, Carolina; Guzman, Fanny; Álvarez Lueje, Alejandro; Kogan Bocian, Marcelo (Sociedad Chilena de Quimica, 2015)
      In this work, we report a fast and accessible method for quantification of cetyltrimethylammonium bromide (CTAB) in solutions of gold nanorods (GNRs) by bromophenol blue (BPB) ion-paring formation and spectrophotometric ...
    • Ionic self-complementarity induces amyloid-like fibril formation in an isolated domain of a plant copper ... 
      Mira, Helena.; Vilar, Marçal; Esteve, Vicent; Martinell, Marc; Kogan Bocian, Marcelo; Giralt, Ernest; Salom, David; Mingarro, Ismael; Peñarrubia, Lola; Pérez Payá, Enrique (BioMed Central Ltd., 2004-06-04)
      Arabidopsis thaliana copper metallochaperone CCH is a functional homologue of yeast antioxidant ATXI, involved in cytosolic copper transport. In higher plants, CCH has to be transported to specialised cells through ...
    • Label-Free Graphene Oxide-Based Surface Plasmon Resonance Immunosensor for the Quantification of Galectin-3, ... 
      Primo, Emiliano N.; Kogan Bocian, Marcelo; Verdejo, Hugo E.; Bollo Dragnic, Soledad; Rubianes, María D.; Rivas, Gustavo A. (American Chemical Society, 2018)
      © 2018 American Chemical Society. We report the first optical biosensor for the novel and important cardiac biomarker, galectin-3 (Gal3), using the anti-Gal3 antibody as a biorecognition element and surface plasmon resonance ...
    • Mechanistic aspects of CPP-mediated intracellular drug delivery: Relevance of CPP self-assembly 
      Pujals, Sílvia; Fernández Carneado, Jimena; López Iglesias, Carmen; Kogan Bocian, Marcelo; Giralt, Ernest (ELSEVIER, 2006-03)
      In recent years, cell-penetrating peptides have proven to be an efficient intracellular delivery system. The mechanism for CPP internalisation, which first involves interaction with the extracellular matrix, is followed ...
    • Metal Nanoparticles for the Treatment and Diagnosis of Neurodegenerative Brain Diseases 
      Vio, Valentina; Marchant, María José; Araya, Eyleen; Kogan Bocian, Marcelo (Bentham Science Publishers Ltd., 2017)
      This review focuses on the application of metal nanoparticles in the diagnosis and treatment of Alzheimer's and Parkinson's diseases. Metal nanoparticles present interesting physicochemical properties that can be applied ...
    • Multifunctionalized gold nanoparticles with peptides targeted to gastrin-releasing peptide receptor of a ... 
      Hosta-Rigau, Leticia; Olmedo, Ivonne; Arbiol, Jordi; Cruz, Luis J.; Kogan Bocian, Marcelo; Albericio, Fernando (2010)
      Functionalization of gold nanoparticles (AuNPs) with both a targeting peptide (an analogue of the peptide Bombesin) and a drug peptide ligand (an analogue of the RAF peptide) with the aim of improving selectivity in the ...
    • Nanoparticle-mediated local and remote manipulation of protein aggregation 
      Kogan Bocian, Marcelo; Bastus, Neus G.; Amigo, Roger; Grillo-Bosch, Dolors; Araya, Eyleen; Turiel, Antonio; Labarta, Amilcar; Giralt, Ernest; Puntes, Víctor F. (AMER CHEMICAL SOC, 2006-01)
      The local heat delivered by metallic nanoparticles selectively attached to their target can be used as a molecular surgery to safely remove toxic and clogging aggregates. We apply this principle to protein aggregates, in ...
    • Nanoparticles for diagnosis and therapy of atherosclerosis and myocardial infarction: Evolution toward ... 
      Bejarano, Julian; Navarro Márquez, Mario F.; Morales Zavala, Francisco; Morales, Javier O.; García Carvajal, Ivonne; Araya Fuentes, Eyleen; Flores, Yvo; Verdejo, Hugo E.; Castro, Pablo F.; Lavandero González, Sergio; Kogan Bocian, Marcelo (Ivyspring International Publisher, 2018)
      © Ivyspring International Publisher. Cardiovascular diseases are the leading cause of death worldwide. Despite preventive efforts, early detection of atherosclerosis, the common pathophysiological mechanism underlying ...
    • Nanopartículas de oro administradas en cerebro de rata : biodistribución y efectos sobre tejido 
      Riquelme Serey, Sebastián Andrés (Universidad de Chile, 2014)
      El uso de las nanopartículas de oro (NpO) ha adquirido importancia en los últimos años en la industria farmacéutica debido a que se han convertido en una herramienta promisoria para el diagnóstico y tratamiento de ...