Now showing items 389-408 of 4817

    • Sandoval, S.; García Nannig, Lorena; Mancilla, Marta; Kettlun, Ana María; Collados, L. E.; Chayet, L.; Alvarez, A.; Traverso Cori, A.; Valenzuela Pedevila, María Antonieta (PERGAMON-ELSEVIER SCIENCE LTD, 1996-05)
      Ecto-nucleotidases may have a role in the regulation of purinoceptor-mediated responses. ATP-diphosphohydrolase or apyrase has been described as an ecto-nucleotidase, which is characterized by a low specificity for its ...
    • Espinosa, Victoria; Galleguillos, M.; Mancilla, Marta; Garrido, J.; Kettlun, Ana María; Collados, L. E.; Chayet, L.; García Nannig, Lorena; Traverso Cori, A.; Valenzuela Pedevila, María Antonieta (ACADEMIC PRESS AUST, 1996-08)
      Extracellular nucleotides interact with specific receptors on the cell surface and are locally metabolized by ecto-nucleotidases. Biochemical characterization of the ATPase and ADPase activities detected in rat heart ...
    • Jiménez, Paula; García Nannig, Lorena; Adarmes, H.; González, E.; Valenzuela, M. A. (2002)
      ATPase and ADPase activities capable of hydrolyzing nucleoside di- and triphosphates in the presence of Ca2+ are present in synovial membrane of metacarpophalangeal joint mainly associated to membrane fractions. These ...
    • Pieber, M.; Valenzuela Pedevila, María Antonieta; Kettlun, Ana María; Mancilla, Marta; Aranda, E.; Collados, L. E.; Traverso Cori, A. (PERGAMON-ELSEVIER SCIENCE LTD, 1991)
      1. Calcium-stimulated ATPase-ADPase activities were studied in a microsomal fraction of rat placental tissue. 2. The kinetic characteristics correspond to those of ATP-diphosphohydrolase, also known as apyrase (E.C. ...
    • Jofré Romeo, Fabián J. (Universidad de ChileCyberDocs, 2010)
      El componente nervioso simpático regula la función ovárica y su actividad nerviosa aumenta al final del periodo reproductivo, lo que supone una relación entre envejecimiento ovárico y aumento del tono simpático. Este ...
    • Pérez Núñez, Ramón Daniel (Universidad de Chile, 2016)
      El Síndrome de Down se define como un desorden del desarrollo causado por la presencia de una copia extra del cromosoma 21, que va acompañado de anomalías multisistémicas principalmente a nivel del sistema nervioso ...
    • Aránguiz Urroz, Pablo Daniel; Contreras Ferrat, Ariel Eduardo; Rojas Rivera, Diego; Troncoso Cotal, Rodrigo Hernán; Marambio Morales, Paola Angélica; Toro, Bárbara; Sanhueza Muñoz, Carlos Joaquín; Pennanen Saavedra, Christian; Díaz Elizondo, Jessica; Parra Ortíz, María Valentina; Chiong Lay, Mario; Díaz Araya, Guillermo; Lavandero González, Sergio (Sociedad Chilena de Cardiología y Cirugía Cardiovascular, 2006)
      Históricamente, la apoptosis y la necrosis han sido consideradas como las dos formas fundamentales de muerte celular. Sin embargo, evidencias recientes sugieren que la muerte celular programada no está confinada sólo a ...
    • Aubourg, Santiago P.; Quitral Robles, Vilma; Larraín Barth, María Angélica; Rodríguez Melis, Alicia; Gómez, Julio; Maier Neumann, Liliana Cristina; Vinagre, Julia (ELSEVIER SCI LTD, 2007)
      Two deteriorative pathways (autolysis and microbiological activity) were studied in farmed Coho salmon (Oncorhynchus kisutch) for 24 days during chilled storage. These changes were assessed by nucleotide degradation ...
    • Murgas, Leandro; Contreras Riquelme, Sebastián; Martínez Hernández, Jesús Eduardo; Villaman, Camilo; Santibáñez, Rodrigo; Martín, Alberto J. M. (Royal Soc, England, 2021)
      The regulation of gene expression is a key factor in the development and maintenance of life in all organisms. Even so, little is known at whole genome scale for most genes and contexts.We propose a method, Tool forWeighted ...
    • Chávez, Myra; Morales, Rodrigo A.; López Crisosto, Camila; Roa, Juan; Allende Connelly, Miguel; Lavandero González, Sergio (Nature, 2020)
      Autophagy is an evolutionarily conserved process that plays a key role in the maintenance of overall cellular health. While it has been suggested that autophagy may elicit cardioprotective and pro-survival modulating ...
    • Hill, Joseph A.; Rothermel, Beverly A.; Lavandero González, Sergio (Elsevier, 2012)
    • Lavandero González, Sergio; Chiong Lay, Mario; Rothermel, Beverly A.; Hill, Joseph A. (American Society for Clinical Investigation, 2015)
      Cardiovascular disease is the leading cause of death worldwide. As such, there is great interest in identifying novel mechanisms that govern the cardiovascular response to disease-related stress. First described in failing ...
    • García Miguel, Marina; Riquelme, Jaime A.; Norambuena Soto, Ignacio; Morales, Pablo E.; Sanhueza Olivares, Fernanda; Núñez Soto, Constanza Belén; Mondaca Ruff, David; Cancino Arenas, Nicole; San Martín, Alejandra; Chiong Lay, Mario (Public library science, 2018)
      Vascular smooth muscle cells (VSMC) dedifferentiation from a contractile to a synthetic phenotype contributes to atherosclerosis. Atherosclerotic tissue has a chronic inflammatory component with high levels of tumor necrosis ...
    • Schmidt Hebbel, Hermann; Pennacchiotti Monti, Irma; Avendaño V., Sonia; Masson Salaué, Lilia; Wittig Rovira, Emma; Amadori M., Enrique (2001)
    • Pennacchiotti Monti, Irma (Colegio Químico Farmacéutico de Chile, A. G., 1989)
      La importancia del tema se debe a la especial relación entre alimentos y enzimas. Las enzimas, catalizadores bioquímicos, cumplen diversas funciones en los alimentos, provocando en algunos casos, graves daños en el color, ...
    • Weiss López, Boris; Miño Galaz, Germán; Araya Maturana, Ramiro; Tracey, Alan S. (AMER CHEMICAL SOC, 2000-04-18)
      Deuterium quadrupole splittings of benzyl alcohol-d(5) and a series of alkyl benzyl-d(5), ethers, with linear aliphatic chains from 1 to 12 carbon atoms, were measured using H-2 NMR spectroscopy. These molecules were ...
    • Weiss López, Boris; Saldaño Hurtado, Danilo; Araya Maturana, Ramiro; Gamboa, Consuelo (AMER CHEMICAL SOC, 1997-12-24)
      Deuterium quadrupole splittings from the aromatic ring of a series of linear benzyl-d(5) alkyl ethers, with alkyl chain length from 1 to 15 carbon atoms, have been measured using H-2-NMR spectroscopy. These molecules, 20% ...
    • Verdugo Leal, Francisco Nicolás (Universidad de Chile, 2022)
      Diversos virus emergentes de orígenes zoonóticos han surgido este último tiempo. Dentro de los más importantes tenemos al virus Influenza A y diferentes coronavirus. Un reservorio para virus de estos géneros son las aves ...