Facultad de Ciencias Químicas y Farmacéuticas: Recent submissions

Now showing items 4501-4520 of 5085

    • Understanding the stereo- and regioselectivities of the polar Diels-Alder reactions between 2-acetyl-1,4- ... 
      Soto Delgado, Jorge; Domingo, L. R.; Araya Maturana, Ramiro; Contreras Ramos, Renato (JOHN WILEY & SONS LTD, 2009-06)
      The polar Diels-Alder (DA) reactions of 2-acetyl-1,4-benzoquinone (acBQ) with methyl substituted 1,3-butadienes have been studied using DFT methods at the B3LYP/6-31 G(d) level of theory. These reactions are characterized ...
    • 8,8-Diethyl-1,4,5,8-tetrahydronaphthalene-1,4,5-trione 
      Vega, Andrés; Ramírez Rodríguez, Oney; Martínez Cifuentes, Maximiliano; Ibáñez, Andrés; Araya Maturana, Ramiro (WILEY-BLACKWELL PUBLISHING, INC, 2009-02)
      The title molecule, C14H14O3, contains two fused six-membered carbon rings with keto groups at positions 1, 4 and 5 and a gem-diethyl group at position 8. The molecule is close to planar (maximum deviation = 0.044 angstrom), ...
    • Adsorption of ochratoxin A (OTA) anodic oxidation product on glassy carbon electrodes in highly acidic ... 
      Ramírez, Eduardo Alejandro; Zon, María Alicia; Jara Ulloa, Paola Andrea; Squella Serrano, Juan; Núñez Vergara, Luis; Fernández, Héctor (PERGAMON-ELSEVIER SCIENCE LTD, 2010-01-01)
      We study the thermodynamics and kinetics of the adsorption of a redox couple having quinone nature on glassy carbon electrodes. This couple is produced by the anodic oxidation of mycotoxin ochratoxin A in 10% acetonitrile ...
    • Rapid Capillary Electrophoresis Analysis of Glutathione and Glutathione Disulfide in Roots and Shoots of ... 
      Mendoza, Jorge; Garrido Reyes, Tatiana Inés; Riveros Salvatierra, Raúl; Parada Aliste, José (JOHN WILEY & SONS LTD, 2009-03)
      Introduction - Glutathione and glutathione disulfide can be determined by capillary zone electrophoresis; however, the frequent use of acidic precipitation of protein from samples prior to analysis generates an acidic ...
    • Two isomorphous crotonatolanthanide complexes: tetra-mu-but-2-enoato-bis[diaqua(but-2-enoato)Ln]-2,6-diaminopurine ... 
      Atria Salas, Ana María; Astete, Alan; Garland, María Teresa; Baggio, Ricardo (WILEY-BLACKWELL PUBLISHING, 2009-11)
      The title isomorphous compounds, tetra-mu-but-2-enoato-bis[diaqua(but-2-enoato)dysprosium(III)]-2,6-diaminopurine (1/2), [Dy-2(C4H5O2)(6)(H2O)(4)]center dot 2C(5)H(6)N(6), and tetra-mu-but-2-enoato-bis[diaqua(but-2-enoat ...
    • Oligo and polyuronic acids interactions with hypervalent chromium 
      González, J. C.; García, S. I.; Bellú, Sebastián; Atria Salas, Ana María; Salas Pelegrin, Juan Manuel; Rockenbauer, A.; Korecz, L.; Signorella, Sandra; Sala, Luis F. (PERGAMON-ELSEVIER SCIENCE LTD, 2009-09-02)
      Selective oxidation of galacturonic residues of oligo and polyuronic acids by Cr-VI affords CO2/HCO2H, oxidized uronic acid, and Cr-III as final redox products. Kinetic studies show that the redox reaction proceeds through ...
    • Modification of poly(propylene) through grafting with dimethyl itaconate in solution 
      Yazdani-Pedram Zobeiri, Mehrdad; Vega, H.; Quijada Abarca, Juan (WILEY-V C H VERLAG GMBH, 1998-11)
      Functionalization of isotactic poly(propylene) (PP) with dimethyl itaconate (DMI) as functional polar monomer using 2,5-dimethyl-2,5 -bis(tert-butylperoxy)hexane (L101) as radical initiator was carried out in both boiling ...
    • Transparent semiconductor-polymer hybrid films with tunable optical properties 
      Martínez, Y.; Retuert de la Torre, Pedro Jaime; Yazdani-Pedram Zobeiri, Mehrdad; Coelfen, H. (ROYAL SOC CHEMISTRY, 2007)
      Size confined CdS nanoparticles with controlled size and narrow particle size distribution were synthesized in transparent adhesive polyelectrolyte films, which are composed of chitosan (CHI), poly( monomethyl itaconate) ...
    • A synthethic overview of new molecules with 5-HT 1A binding affinities 
      Pessoa Mahana, Hernán; Araya Maturana, Ramiro; Saitz Barría, Claudio; Pessoa, D. (Bentham Science Publishers, Ltd, 2003)
      The present review discusses the synthetic strategies of new ligands exhibiting mainly 5-HT1A binding affinities. Specifically we focused our attention in the synthesis of compounds structurally telated to arylpiperazine, ...
    • Synthesis of N-(morpholinomethyl) benzamides as moclobemide analogs 
      Pessoa Mahana, Hernán; Astudillo, C. I.; Araya Maturana, Ramiro (MARCEL DEKKER INC, 2002)
      Syntheses of new morpholinomethylbenzamides 6 bearing both electron-withdrawing and electron-releasing groups at the aromatic ring are described. The strategy involved synthesis of hippuric acid ethyl esters 3, their ...
    • Synthesis of benzo[b]thiophene carboxamides connected to 4-arylpiperazines through a benzylic spacer: ... 
      Pessoa Mahana, Hernán; Acevedo Ramos, Armando Rodrigo; Araya Maturana, Ramiro; Saitz Barría, Claudio; Pessoa, D. (TAYLOR & FRANCIS INC, 2007)
      New benzothiophene arylpiperazine derivatives 8 (a-f) were synthesized as potential serotoninergic agents with 5-HT1A receptor affinity. Preparation of the derivatives was performed by treating N-[2-(chloromethyl)phenyl] ...
    • Synthesis of 4-arylpiperazine derivatives of moclobemide: Potential antidepressants with a dual mode of action 
      Pessoa Mahana, Hernán; Recabarren Gajardo, Gonzalo Iván; Araya Maturana, Ramiro; Kosche Cárcamo, Johann Albert; Pessoa, D. (MARCEL DEKKER INC, 2004-07)
      We report here the synthesis of substituted 4-chloro-N-[3-oxo-3-(4-aryl-1-piperazinyl)-propyl] benzamides (5-9), as potential new antidepressants, incorporating in a single molecule structural moieties related to a dual ...
    • Synthesis of 2-benzothienyl carbonyl 4-arylpiperazines as novel delavirdine analogs 
      Pessoa Mahana, Hernán; Acevedo Ramos, Armando Rodrigo; Saitz Barría, Claudio; Araya Maturana, Ramiro; Pessoa, D. (TAYLOR & FRANCIS INC, 2007)
      A novel series of 2-benzothienyl carbonyl arylpiperazines (6a-f) was synthesized as potential HIV nonnucleoside reverse transcriptase inhibitors (NNRTIs). Preparation of the derivatives was performed by reacting benzo[b]thiophene ...
    • Synthesis of 1-benzazepines as precursors of 1-benzazepinediones 
      Pessoa Mahana, Hernán; Valderrama Guerrero, Jaime Adolfo (MARCEL DEKKER INC, 2000)
      The synthesis of 6-hydroxy-7-nitro-1-benzazepine-2-one 7 from 5-hydroxy-1 -tetralone 1 and 6-hydroxy-1 -benzazepine-2-one 2 is described. Bromination of 6-hydroxy- 1-benzazepine-2-one 2 with NBS in ethyl acetate afforded ...
    • Studies on quinones. Part 36. Synthesis and trypanocidal activity of 2-alkoxycarbonylbenzo[b]thiophene-4,7-quinones 
      Pessoa, D.; Valderrama Guerrero, Jaime Adolfo; Olmos, María G.; Espinoza, Omar; Pessoa Mahana, Hernán; Rojas de Arias, Antonieta; Nakayama, Héctor; Torres, Susana; Miret, Jorge (FREUND PUBLISHING HOUSE LTD, 2002)
      A series of 2-alkoxycarbonylbenzo[b]thiophene-4,7-quinones (11-15), prepared from the corresponding acid 5, were tested in vitro against trypomastigote form of Trypanosome cruzi. The influence of the lypophilia and oxidant ...
    • Solvent-free synthesis of 6-arylbenzimidazo[1,2-c]quinazolines under microwave irradiation 
      Pessoa Mahana, Hernán; Pessoa, D.; Salazar González, Ricardo Andrés; Valderrama Guerrero, Jaime Adolfo; Sáez, Edmundo; Araya Maturana, Ramiro (GEORG THIEME VERLAG KG, 2004-02-18)
      The syntheses of 2-(2-nitrophenyl)-1-benzoyl-1H-benzimidazole derivatives 5-9 and their reduction to the corresponding 2-benzimidazoylbenzamides 10-13 are described. Compounds 10-13 were cleanly and efficiently converted ...
    • Solvent-free microwave-promoted Michael addition of aza-nucleophiles to benzo[b] thiophen-2-yl-2-propenone 
      Pessoa Mahana, Hernán; González, Marcos; González, Marcelo; Pessoa, D.; Araya Maturana, Ramiro; Ron Higuera, Nadia Betsabé; Saitz Barría, Claudio (ARKAT USA INC, 2009)
      A series of Michael adducts (5-11) have been synthesized with good yields under solvent-free microwave conditions. Aliphatic and aromatic amines utilized as Michael donors reacted with 1-(4,7-dimethoxybenzo[b] thiophen-2 ...
    • Microwave-assisted synthesis and regioisomeric structural elucidation of novel benzimidazo[1,2d][1,4]benz ... 
      Pessoa, D.; Espinosa Bustos, Christian; Mella Raipán, Jaime A.; Canales Pacheco, Jorge; Pessoa Mahana, Hernán (ARKAT USA INC, 2009)
      The synthesis of 5H-benzimidazo [1,2-d] [1,4] benzodiazepin -6(7H)-ones 3a-e from readily available 2-(2-aminophenyl)-1H-benzo[d]imidazole derivatives 2a-e and 2-bromoacetyl bromide under microwave conditions is described. ...
    • Effects of 4,4-dimethyl-5,8-dihydroxynaphtalene-1-one and 4,4-dimethyl-5,8-dihydroxytetralone derivatives ... 
      Araya Maturana, Ramiro; Delgado Castro, Tomás; Gárate, M.; Ferreira Parker, Jorge; Pavani, M.; Pessoa Mahana, Hernán; Cassels Niven, Bruce (PERGAMON-ELSEVIER SCIENCE LTD, 2002-09)
      A set of structurally related compounds incorporating a carbonyl group in the ortho position with regard to a phenol function were tested against the TA3 mouse carcinoma cell line and its multidrug-resistant variant ...
    • A facile approach for new dibenzo [b,f][1,5] diazocinones 
      Pessoa Mahana, Hernán; Martínez Aranguiz, Gracia Karen; Araya Maturana, Ramiro; Pessoa, D. (TAYLOR & FRANCIS INC, 2005)
      The synthesis of new eight-membered cycle dibenzo[b,f][1,5]-diazocine-6(5H)-one derivatives 11, 12 was developed. The key step in this synthesis was the intramolecular cyclization of the amino aldehyde precursors 9,10 ...