Now showing items 3941-3960 of 4968

    • Stadler, Richard; Loeffler, Susane; Cassels Niven, Bruce; Zenk, Meinhart H. (Pergamon Press plc., 1988-01-27)
      Bisbenzylisoquinoline alkaloid-producing cell cultures of Berberis stolonifera were fed with 14C-Iabelled tyrosine, tyramine, and several chiral l-benzyl-l,2,3,4-tetrahydroisoquinolines. Berbamunine subsequently isolated from ...
    • Stadler, R.; Kutchan, T. M.; Loeffler, S.; Nagakura, N.; Cassels Niven, Bruce; Zenk, Meinhart H. (Pergamon Journals Ltd., 1986-12-18)
      Precursor feeding experiments to Annona reticulata leaves demonstrated that coclaurine and reticuline are both derived from the common lntermediate norcoclaurine; furthermore (S)-coclaurlne was found to be the speciflc ...
    • Squella Serrano, Juan; Cassels Niven, Bruce; Arata, M.; Bavestrello, M. P.; Núñez Vergara, Luis (Pergamon Press Ltd., 1993-03-23)
      Four amphetamine derivatives bearing a methylenedioxy group at positions 3 and 4 of the benzene ring and differing in their substitution at C(6) were studied by differential pulse voltammetry in aqueous media. These ...
    • Sepúlveda Boza, Silvia; Delhvi, Sualaheen; Koch, B.; Zilliken, Federico; Cassels Niven, Bruce (Elsevier , Science Ltd., 1992-11-02)
    • Sepúlveda, Silvia; Delhvi, Sualaheen; Zilliquen, F.; Cassels Niven, Bruce (Elsevier Science Inc., 1992-11-02)
    • Sepúlveda Boza, Silvia; Delhvi, Sualaheen; Cassels Niven, Bruce (Pergamon Press, 1989-09-06)
      The stem bark of Persea lingue afforded a new aryltetralin lignan, named lingueresinol, which was shown to be a positional isomer of epi-lyoniresinol.
    • Cassels Niven, Bruce; Sepúlveda Boza, Silvia (Laboratorios Mixim S.A., 1988)
      Se describe la síntesis de una serie de 2-aril-l,3-dinitropropanos por condensación de benzaldehidos con nitrometano. Estos compuestos tienen utilidad potencial como precursores de 2-aril-1,3-dinitropropanos, los que ...
    • Cassels Niven, Bruce; Sepúlveda Boza, Silvia (Sociedad Chilena de Química, 1990-04-16)
      La bromación del 2,5-dimetoxibenzaldehído en ácido acético dió 4-bromo2,5- dimetoxi-y 2-bromo-3,6-dimetoxibenzaldehído en una razón de 4:1. El primero de éstos sufrió sustituciones nucleofilicas con tioles en DMF ...
    • Scorza, Ma. Cecilia; Carrau, Cecilia; Silveira, Rodolfo; Zapata-Torres, Gerald; Cassels Niven, Bruce; Reyes Parada, Miguel (Elsevier Science Inc., 1997)
      The monoamine oxidase (MAO) inhibitory propenies of a series of amphetamine derivatives with difTerent substituents at or around rhe para position of the aromaric ring were evaluateJ. i¡, in viero stuJies in which a crude ...
    • Saez, Patricio; Borges, Yolanda; González, Ernesto; Cassels Niven, Bruce (Elsevier , Science Ltd., 1993-02-16)
      I, 2C·fI 12'(2,5.dimelhoxYJ'hcny1)elhyl;mlil1cj (1'°1 ." Ií, 7-1),1 1\II'F,\ pp,1,.~. trlmelhoxyphenyl)elhylnl11il1el (pDz = 5.81). ,c·n (2(2,5 ditnrfh,,:(y.-1I11f:lhylpIH~lIy')("',yl:"I1II1('1 (pO, = 5.06), homovelalrylnmlne ...
    • Squella Serrano, Juan; Berguecio, María; Hernández, A.; Cassels Niven, Bruce; Núñez Vergara, Luis (Elsevier , Science Ltd., 1991-11-26)
      A set of 2,5-dimethoxyamphetarnines differing in their substitution at C4 was studied by differential pulse voltammetry and linear scan cyclic voltammetry in aqueous media. These experiments showed a single oxydation ...
    • Speisky Cosoy, Hernán; Cassels Niven, Bruce; Lissi Gervaso, Eduardo A.; Videla Cabrera, Luis (Pergamon Press, 1990-11-30)
      Boldine, in low micromolar concentrations, was able to prevent brain bomogenate autooxidatíon, the 2,2'·uobis(2·amidinopropane)(AAP)·induced Iipid peroxidation of red cell plasma rnembranes, and the AAP·induced inactivation ...
    • Sepúlveda Boza, Silvia; Cassels Niven, Bruce (Laboratorios Mixim, S.A., 1979)
      SOJlhork'".ide .,..1 \-al.led In 2,3~ yi.ld 'rom IlI&Vft 01 SclliIJIIS I.,jfoUlIs (An.c.rdl.c •• e), used u a lolk ~unlr.~épliv,. Thi. compoulld mi)' be relpon.lblc '01 Ihe plent', .ttrlhuted llltif,nill1y pmpel1lí1,
    • Rojas, Evelyn; Norambuena, Ester; Olea Azar, Claudio; Reyes Parada, Miguel; Cassels Niven, Bruce (Sociedad Chilena de Química, 1993-10-15)
      The electrochemistry 01 a series 01 monoamine oxidase-inhibitory 4-Nmethyl and N,N-dimethylaminophenethylamines was studied using cyclic voltammetry. Electron transler was irreversible both in aqueous buffer.(pH = 7.4) and ...
    • Torres, Milton A.; Rezendé, Marcos C.; Cassels Niven, Bruce (EIsevier Science Inc., 1997-10-03)
      1. Ten racemic ~-alkoxy-~-phenylethylamines were found to elicit concentrationdependent contraction of the isolated rat thoracic aorta with apparent pD2 values in the 4.56-6.76 range. With one exception, which produces ...
    • Reyes Parada, Miguel; Scorza, Cecilia; Silveira, Rodolfo; Dajas, Federico; Cassels Niven, Bruce (Elsevier , Science Ltd., 1994-04-04)
      4-Dimethylaminophenethylamine (DMAPEA) was characterized as an MAO substrate. This compound was unaffected by MAO-A, while its oxidation by MAO-B was linear as a function of both time and enzyme concentration, with Km = ...
    • Saavedra Aguilar, Juan Carlos; Gómez Jeria, Juan; Morales L., Demián (Sociedad de Neurología, Psiquiatría y Neurocirugía, 1989)
      En este trabajo se analiza el conocimiento actual sobre los receptores o y PCP/NMDA. Se enfatiza que el haloperidol y muchos otros antipsicóticos similares presentan una afinidad relativamente alta por el receptor o. ...
    • Reyes Parada, Miguel; Scorza, Ma. Cecilia; Silveira, Rodolfo; Dajas, Federico; Cassels Niven, Bruce (EIsevier Science Ltd., 1994-04-04)
      4-Dimethylaminophenethylamine (DMAPEA) was characterized as an MAO substrate. This compound was unaffected by MAO-A, while its oxidation by MAO-B was linear as a function of both time and enzyme concentration, with Km = ...
    • Reyes Parada, Miguel; Scorza, Ma Cecilia; Silveira, Rodolfo; Dajas, Federico; Costa, Gustavo; Tipton, Keith F.; Cassels Niven, Bruce (Elsevier Science Ltd., 1993-11-13)
      The in vitra and ex viva monoamine oxidase (MAO) inhibitory effects of (±)4-dimethylaminoa- methyl-phenethylamine (4-DMAA) and (± )4-methylamino-a-methyl-phenethylamine (4-MAA) were reassessed, in comparison with the ...
    • Cárdenas Jirón, G. I.; Figueroa, K. A.; Vargas C., V.; Gómez Jeria, Juan; Campos Vallette, Marcelo (Marcel Dekker. Inc., 1987-04-11)
      Thymine dimers were obtained under ultraviolet irradiation. The major product is a trans-anti dimer linked by a cyclobutane ring. The infrared assignments and the mechanism of formation of this dimer are discussed in ...