Facultad de Ciencias Químicas y Farmacéuticas: Recent submissions

Now showing items 541-560 of 4850

    • Strategies of elicitation to enhance bioactive compound content in edible plant sprouts: a bibliometric study 
      Toro, María Trinidad; Ortiz Viedma, Jaime Alejandro; Becerra, José; Zapata, Nelson; Fierro, Paulo; Illanes, Marcelo; López, María Dolores (MDPI, 2021)
      Vegetable sprouts are a food source that presents high content of bioactive compounds which can also be enhanced through elicitation mechanisms. To better understand the scientific production and research trends on this ...
    • Theobroma cacao L. compounds: Theoretical study and molecular modeling as inhibitors of main SARS-CoV-2 protease 
      Yáñez Osses, Osvaldo Andrés; Osorio, Manuel Isaías; Areche Medina, Carlos Alberto; Vásquez Espinal, Alejandro; Bravo, Jéssica; Sandoval Aldana, Angélica; Pérez Donoso, José M.; González Nilo, Fernando Danilo; Matos, María Joao; Osorio, Edison; García Beltrán, Olimpo José; Tiznado Vásquez, William Artemio (Elsevier, 2021)
      Cocoa beans contain antioxidant molecules with the potential to inhibit type 2 coronavirus (SARS-CoV-2), which causes a severe acute respiratory syndrome (COVID-19). In particular, protease. Therefore, using in silico ...
    • Protective effect of red algae (Rhodophyta) extracts on essential dietary components of heat-treated salmon 
      Ortiz Viedma, Jaime Alejandro; Aguilera, José M.; Flores, Marcos; Lemus Mondaca, Roberto Alejandro; Larrazabal Fuentes, María José; Miranda, José M.; Aubourg Martin, Santiago Pedro (MDPI, 2021)
      Salmon paste contains nutritious components such as essential fatty acids (EPA, DHA), vitamin E and astaxanthin, which can be protected with the addition of red algae extracts. Phenolic extracts were prepared with an ...
    • Editorial: Mitochondrial remodeling and dynamic inter-organellar contacts in cardiovascular physiopathology 
      Santulli, Gaetano; Monaco, Giovanni; Parra Ortiz, Valentina Maria; Morciano, Giampaolo (Frontiers Media, 2021)
    • Development of a multiplex PCR assay for genotyping the fish pathogen piscirickettsia salmonis through ... 
      Isla, Adolfo; Martínez Hernández, Jesús Eduardo; Levipan, Héctor A.; Haussmann, Denise; Figueroa, Jaime; Rauch, María Cecilia; Maracaja Coutinho, Vinicius; Yáñez, Alejandro (Frontiers Media SA, 2021)
      Piscirickettsia salmonis is a bacterial pathogen that severely impact the aquaculture in several countries as Canada, Scotland, Ireland, Norway, and Chile. It provokes Piscirickettsiosis outbreaks in the marine phase of ...
    • A case-control study of a combination of single nucleotide polymorphisms and clinical parameters to predict ... 
      Córdova Delgado, Miguel Angel; Bravo, María Loreto; Cumsille, Elisa; Hill, Charlotte N.; Muñoz Medel, Matías; Pinto, Mauricio P.; Retamal, Ignacio N.; Lavanderos, María; Miquel, Juan Francisco; Rodríguez Fernández, María (BMC, 2021)
      Background: Fluoropyrimidine plus platinum chemotherapy remains the standard first line treatment for gastric cancer (GC). Guidelines exist for the clinical interpretation of four DPYD genotypes related to severe ...
    • Edible oil parameters during deterioration processes 
      Flores, Marcos; Avendaño, Victoria; Bravo, Jessica; Valdés, Cristian; Forero Doria, Óscar; Quitral, Vilma; Vilcanqui, Yesica; Ortiz Viedma, Jaime Alejandro (Hindawi, 2021)
      With the continuous increase in research on lipids, technologies and the development of chemical-analytical methods associated with the characterization and monitoring of different processes that involve modifications in ...
    • Effect of storage conditions on the quality of arbequina extra virgin olive oil and the impact on the ... 
      Caipo Coral, Leeanny Johary; Sandoval Paredes, Ana Maria; Sepúlveda, Betsabet; Fuentes Pérez, Edwar; Valenzuela Baez, Rodrigo Wladimir; Metherel, Adam H.; Romero Palacios, Nalda Marcela (MDPI, 2021)
      Commercialization of extra virgin olive oil (EVOO) requires a best before date recommended at up to 24 months after bottling, stored under specific conditions. Thus, it is expected that the product retains its chemical ...
    • MicroRNA-335-5p is a potential suppressor of metastasis and invasion in gastric cancer (vol 9, 114, 2017) 
      Sandoval Bórquez, Alejandra; Polakovicova, Iva; Carrasco Véliz, Nicolás; Lobos González, Lorena; Riquelme, Ismael; Carrasco Avino, Gonzalo; Bizama Soto, Carolina del Carmen; Norero, Enrique; Owen, Gareth I.; Roa Strauch, Juan Carlos; Corvalán, Alejandro H. (BMC, 2021)
    • Associations of six adiposity-related markers with incidence and mortality from 24 cancers—findings from ... 
      Parra Soto, Solange Liliana; Cowley, Emma S.; Rezende, Leandro F. M.; Ferreccio Keadi, Catterina; Mathers, John C.; Pell, Jill P.; Ho, Frederick K.; Celis Morales, Carlos (BMC, 2021)
      Background: Adiposity is a strong risk factor for cancer incidence and mortality. However, most of the evidence available has focused on body mass index (BMI) as a marker of adiposity. There is limited evidence on ...
    • New quinone antibiotics against methicillin-resistant S. aureus 
      Campanini Salinas, Javier Andrés; Andrades Lagos, Juan Andrés; Hinojosa Torres, Nicolás Antonio; Moreno Ruz, Fabián Eduardo; Alarcón, Pedro; González Rocha, Gerardo; Burbulis, Ian E.; Vásquez Velásquez, David (MDPI, 2021)
      There is an urgent need for the development of new antibiotics. Here, we describe the inhibitory activity of new quinone compounds against methicillin-resistant Staphylococcus aureus (ATCC(R) 43300), methicillin-sensitive ...
    • Toll-like receptor 4 activation prevents rat cardiac fibroblast death induced by simulated ischemia/reperfusion 
      Parra Flores, Pablo Ignacio; Espitia Corredor, Jenaro Antonio; Espinoza Pérez, Claudio Andrés; Queirolo, Cristian; Ayala, Pedro; Brüggendieck, Francisca; Salas Hernández, Aimee; Pardo Jiménez, Viviana Gladys; Díaz Araya, Guillermo Antonio (Frontiers Media, 2021)
      Death of cardiac fibroblasts (CFs) by ischemia/reperfusion (I/R) has major implications for cardiac wound healing. In in vivo models of myocardial infarction, toll-like receptor 4 (TLR4) activation has been reported as ...
    • Thermal behavior improvement of fortified commercial avocado (persea americana Mill.) oil with maqui ... 
      Flores, Marcos; Reyes García, Luis; Ortiz Viedma, Jaime Alejandro; Romero Palacios, Nalda Marcela; Vilcanqui Chura, Yesica Luz; Rogel, Cristian; Echeverría, Javier; Forero Doria, Óscar (MDPI, 2021)
      Avocado oil is considered a highly prized food due to its nutritional contribution. On the other hand, Aristotelia chilensis (Molina) Stuntz (Elaeocarpaceae), common name “maqui”, is an endemic fruit in Chile, well known ...
    • Preliminary investigation of different drying systems to preserve hydroxytyrosol and its derivatives in ... 
      López Salas, Lucía; Cea, Inés; Borrás Linares, Isabel; Emanuelli, Tatiana; Robert Canales, Paz Soledad; Segura Carretero, Antonio; Lozano Sánchez, Jesús (MDPI, 2021)
      Phenolic compounds present in extra virgin olive oil (EVOO) could be retained in its byproducts during processing. Among them, hydroxytyrosol and its derivatives deserve special attention due to their health benefits ...
    • Outbreak: a user‑friendly georeferencing online tool for disease surveillance 
      Arias Carrasco, Raúl Rubén; Giddaluru, Jeevan; Cardozo, Lucas E.; Martins Moraes, Felipe; Maracaja Coutinho, Vinicius; Nakaya, Helder I. (Sociedad de Biología de Chile, 2021)
      The current COVID-19 pandemic has already claimed more than 3.7 million victims and it will cause more deaths in the coming months. Tools that track the number and locations of cases are critical for surveillance and help ...
    • Endoplasmic reticulum-mitochondria coupling increases during doxycycline-induced mitochondrial stress in HeLa cells 
      López Crisosto, Camila Paz; Díaz Vegas, Alexis; Castro, Pablo F.; Rothermel, Beverly A.; Bravo Sagua, Roberto Francisco; Lavandero González, Sergio Alejandro (SpringerNature, 2021)
      Subcellular organelles communicate with each other to regulate function and coordinate responses to changing cellular conditions. The physical-functional coupling of the endoplasmic reticulum (ER) with mitochondria allows ...
    • Polycystin-1 is required for insulin-like growth factor 1-induced cardiomyocyte hypertrophy 
      Fernández, Carolina; Torrealba, Natalia; Altamirano, Francisco; Garrido Moreno, Valeria Soraya; Vásquez Trincado, César; Flores Vergara, Raúl Alejandro; López Crisosto, Camila; Ocaranza, María Paz; Chiong Lay, Mario Martin; Pedrozo Cibils, Zully Rocío Evangelina; Lavandero González, Sergio (Public Library Science, 2021)
      Cardiac hypertrophy is the result of responses to various physiological or pathological stimuli. Recently, we showed that polycystin-1 participates in cardiomyocyte hypertrophy elicited by pressure overload and mechanical ...
    • Oligoarginine peptide conjugated to BSA improves cell penetration of gold nanorods and nanoprisms for ... 
      Bolaños, Karen; Sánchez Navarro, Macarena; Tapia Arellano, Andreas; Giralt, Ernest; Kogan, Marcelo Javier; Araya, Eyleen (MDPI, 2021)
      Gold nanoparticles (AuNPs) have been shown to be outstanding tools for drug delivery and biomedical applications, mainly owing to their colloidal stability, surface chemistry, and photothermal properties. The biocompatibility ...
    • Determination of antioxidant activity by Oxygen Radical Absorbance Capacity (ORAC-FL), Cellular Antioxidant ... 
      Pilaquinga, Fernanda; Morey, Jeroni; Fernández, Lenys; Espinoza Montero, Patricio; Moncada Basualto, Mauricio Javier; Pozo Martínez, Josué Santiago; Olea Azar, Claudio Alberto; Bosch, Rafael; Meneses, Lorena; Debut, Alexis; Piña, María de las Nieves (Dove Medical, 2021)
      Purpose: The importance of studying polyphenolic compounds as natural antioxidants has encouraged the search for new methods of analysis that are quick and simple. The synthesis of silver nanoparticles (AgNPs) using plant ...
    • A phenolic-rich extract from ugni molinae berries reduces abnormal protein aggregation in a cellular model ... 
      Pérez Arancibia, Rodrigo Nicolás; Ordóñez, José Luis; Rivas, Alexis; Pihán, Philippe; Sagredo, Alfredo; Ahumada, Ulises; Barriga, Andrés; Seguel, Ivette; Cárdenas, César; Vidal, René L.; Hetz Flores, Claudio Andres; Delporte Vergara, Carla Luz (Public Library Science, 2021)
      Accumulation of misfolded proteins in the brain is a common hallmark of most age-related neurodegenerative diseases. Previous studies from our group identified the presence of anti-inflammatory and antioxidant compounds ...